PARP Targeted Alpha-Particle Therapy Enhances Response to PD-1 Immune-Checkpoint Blockade in a Syngeneic Mouse Model of Glioblastoma.
Journal
ACS pharmacology & translational science
ISSN: 2575-9108
Titre abrégé: ACS Pharmacol Transl Sci
Pays: United States
ID NLM: 101721411
Informations de publication
Date de publication:
12 Feb 2021
12 Feb 2021
Historique:
received:
02
12
2020
entrez:
22
2
2021
pubmed:
23
2
2021
medline:
23
2
2021
Statut:
epublish
Résumé
We have previously demonstrated potent antitumor effects of PARP targeted alpha-therapy with astatine-211-MM4 ([
Identifiants
pubmed: 33615184
doi: 10.1021/acsptsci.0c00206
pmc: PMC7887847
doi:
Types de publication
Journal Article
Langues
eng
Pagination
344-351Subventions
Organisme : NCI NIH HHS
ID : R01 CA219006
Pays : United States
Informations de copyright
© 2021 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare the following competing financial interest(s): R.H.M., D.A.P., and M.M. are inventor and co-inventors on a pending patent for a 211At-PARP targeted radiotherapy. All other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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