The Advantage of Pinpoint Camera System With Indocyanine Green for Sentinel Lymph Node Micrometastasis Detection in Low Risk Endometrial Cancer.


Journal

In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809

Informations de publication

Date de publication:
Historique:
received: 29 09 2020
revised: 09 12 2020
accepted: 15 12 2020
entrez: 24 2 2021
pubmed: 25 2 2021
medline: 22 6 2021
Statut: ppublish

Résumé

This report outlines our experience in the management of 10 cases of low-risk endometrial cancer with Indocyanine Green for sentinel lymph node (SLN) mapping using the Pinpoint 30-degree 4K S1 SPY real-time camera system (Stryker). This system offers simultaneous, real-time, high-definition white light and fluorescence imaging through a single laparoscope, without the need to change camera filters. In our retrospective case series we included all endometrioid endometrial cancers of grade G1 and pre-operative radiological staging FIGO 1A reported on magnetic resonance imaging (MRI) that were treated laparoscopically from October 2019 to April 2020. Bilateral sentinel lymph node excision was achieved in 9 out of 10 cases. In one patient, one sentinel lymph node featuring a micrometastasis of <2 mm was identified. A specialist minimal access team can safely and reliably reproduce this technique for sentinel lymph node excision.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
This report outlines our experience in the management of 10 cases of low-risk endometrial cancer with Indocyanine Green for sentinel lymph node (SLN) mapping using the Pinpoint 30-degree 4K S1 SPY real-time camera system (Stryker). This system offers simultaneous, real-time, high-definition white light and fluorescence imaging through a single laparoscope, without the need to change camera filters.
PATIENTS AND METHODS METHODS
In our retrospective case series we included all endometrioid endometrial cancers of grade G1 and pre-operative radiological staging FIGO 1A reported on magnetic resonance imaging (MRI) that were treated laparoscopically from October 2019 to April 2020.
RESULTS RESULTS
Bilateral sentinel lymph node excision was achieved in 9 out of 10 cases. In one patient, one sentinel lymph node featuring a micrometastasis of <2 mm was identified.
CONCLUSION CONCLUSIONS
A specialist minimal access team can safely and reliably reproduce this technique for sentinel lymph node excision.

Identifiants

pubmed: 33622899
pii: 35/2/1033
doi: 10.21873/invivo.12347
pmc: PMC8045059
doi:

Substances chimiques

Coloring Agents 0
Indocyanine Green IX6J1063HV

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1033-1039

Informations de copyright

Copyright© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

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Auteurs

Alexandros Lazaridis (A)

Department of Gynecologic Endoscopy, Lefkos Stavros Hospital, Athens, Greece; alexanderlazaridis@hotmail.com.
Royal London Hospital, Barts Health NHS Trust, London, U.K.

Stylianos Kogeorgos (S)

Department of Gynecologic Endoscopy, Lefkos Stavros Hospital, Athens, Greece.

Panagiotis Balinakos (P)

Department of Gynecologic Endoscopy, Lefkos Stavros Hospital, Athens, Greece.

Kitty Pavlakis (K)

HBD Pathology Lab, Athens, Greece.

Theofani Gavresea (T)

Biopath Innovations, Athens, Greece.

George Pistofidis (G)

Department of Gynecologic Endoscopy, Lefkos Stavros Hospital, Athens, Greece.

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Classifications MeSH