Journal

Chemical Society reviews
ISSN: 1460-4744
Titre abrégé: Chem Soc Rev
Pays: England
ID NLM: 0335405

Informations de publication

Date de publication:
26 Apr 2021
Historique:
pubmed: 25 2 2021
medline: 25 2 2021
entrez: 24 2 2021
Statut: ppublish

Résumé

Nanopores in solid-state membranes are promising for a wide range of applications including DNA sequencing, ultra-dilute analyte detection, protein analysis, and polymer data storage. Techniques to fabricate solid-state nanopores have typically been time consuming or lacked the resolution to create pores with diameters down to a few nanometres, as required for the above applications. In recent years, several methods to fabricate nanopores in electrolyte environments have been demonstrated. These in situ methods include controlled breakdown (CBD), electrochemical reactions (ECR), laser etching and laser-assisted controlled breakdown (la-CBD). These techniques are democratising solid-state nanopores by providing the ability to fabricate pores with diameters down to a few nanometres (i.e. comparable to the size of many analytes) in a matter of minutes using relatively simple equipment. Here we review these in situ solid-state nanopore fabrication techniques and highlight the challenges and advantages of each method. Furthermore we compare these techniques by their desired application and provide insights into future research directions for in situ nanopore fabrication methods.

Identifiants

pubmed: 33623941
doi: 10.1039/d0cs00924e
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

4974-4992

Subventions

Organisme : Medical Research Council
ID : MR/S032541/1
Pays : United Kingdom

Auteurs

Jasper P Fried (JP)

Department of Materials, University of Oxford, Oxford, OX1 3PH, UK.

Jacob L Swett (JL)

Department of Materials, University of Oxford, Oxford, OX1 3PH, UK.

Binoy Paulose Nadappuram (BP)

Department of Chemistry, Imperial College London, Molecular Science Research Hub, White City Campus, 82 Wood Lane, W12 0BZ, UK.

Jan A Mol (JA)

School of Physics and Astronomy, Queen Mary University of London, Mile End Road, E1 4NS, UK.

Joshua B Edel (JB)

Department of Chemistry, Imperial College London, Molecular Science Research Hub, White City Campus, 82 Wood Lane, W12 0BZ, UK.

Aleksandar P Ivanov (AP)

Department of Chemistry, Imperial College London, Molecular Science Research Hub, White City Campus, 82 Wood Lane, W12 0BZ, UK.

James R Yates (JR)

Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157 Oeiras, Portugal. jyates@itqb.unl.pt.

Classifications MeSH