The role of lysosomal ion channels in lysosome dysfunction.
BK
Lysosome
NLRP3
TMEM175
TRPML1
autophagy
crystalline silica
lysosomal membrane permeability
Journal
Inhalation toxicology
ISSN: 1091-7691
Titre abrégé: Inhal Toxicol
Pays: England
ID NLM: 8910739
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
pubmed:
26
2
2021
medline:
21
1
2022
entrez:
25
2
2021
Statut:
ppublish
Résumé
Lysosomes offer a unique arrangement of degradative, exocytic, and signaling capabilities that make their continued function critical to cellular homeostasis. Lysosomes owe their function to the activity of lysosomal ion channels and transporters, which maintain concentration gradients of H
Identifiants
pubmed: 33627009
doi: 10.1080/08958378.2021.1876188
doi:
Substances chimiques
Inflammasomes
0
Ion Channels
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
41-54Subventions
Organisme : NIEHS NIH HHS
ID : R01 ES023209
Pays : United States