Tuberculosis screening after detection of a case in a paediatric haemato-oncology unit in a low prevalence country.
Cribado
Haemato-oncology
Hematooncología
Pacientes pediátricos
Paediatrics
Screening
Tuberculosis
Journal
Enfermedades infecciosas y microbiologia clinica (English ed.)
ISSN: 2529-993X
Titre abrégé: Enferm Infecc Microbiol Clin (Engl Ed)
Pays: Spain
ID NLM: 101777541
Informations de publication
Date de publication:
21 Feb 2021
21 Feb 2021
Historique:
received:
15
09
2020
revised:
14
12
2020
accepted:
17
12
2020
entrez:
25
2
2021
pubmed:
26
2
2021
medline:
26
2
2021
Statut:
aheadofprint
Résumé
There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected. After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8-12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up. After 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients. The TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations.
Sections du résumé
BACKGROUND
BACKGROUND
There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected.
METHODS
METHODS
After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8-12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up.
RESULTS
RESULTS
After 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients.
CONCLUSIONS
CONCLUSIONS
The TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations.
Identifiants
pubmed: 33627247
pii: S0213-005X(21)00022-7
doi: 10.1016/j.eimc.2020.12.017
pii:
doi:
Types de publication
Journal Article
Langues
eng
spa
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2021 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Publicado por Elsevier España, S.L.U. All rights reserved.