Adenoid cystic carcinoma and chronic lymphocytic leukaemia: synchronous presentations in the lung.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
24 Feb 2021
Historique:
entrez: 25 2 2021
pubmed: 26 2 2021
medline: 15 5 2021
Statut: epublish

Résumé

A 59-year-old male active smoker presented with a 6-month history of cough and breathlessness and was found to have a right upper lobe mass. Histology revealed this to be an adenoid cystic carcinoma (ACC) of the lung, while local lymph node dissection revealed a synchronous diagnosis of chronic lymphocytic leukaemia (CLL). The connection between CLL and solid organ malignancy is well documented, but the reporting of ACC in this context is novel. Mechanisms linking the two processes are revealed with the possibility of causality, and heightened vigilance for the development of primary lung tumours in CLL, and their management, is recommended.

Identifiants

pubmed: 33627346
pii: 14/2/e236074
doi: 10.1136/bcr-2020-236074
pmc: PMC7919549
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Philip S Webb (PS)

Oncology and Haematology Directorate, Oxford University Hospitals NHS Foundation Trust, Oxford, UK pwebb1@doctors.org.uk.

Yu Zhi Zhang (YZ)

Department of Histopathology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.

Kirsten Burrell (K)

Department of Radiotherapy, Royal Berkshire NHS Foundation Trust, Reading, UK.

Georges Sinclair (G)

Department of Oncology, Royal Berkshire NHS Foundation Trust, Reading, UK.
Department of Neurosurgery, Bezmialem Vakif University, Istanbul, Turkey.

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