Extracellular Vesicles and Immune System in Ageing and Immune Diseases.
Ageing
Biomarkers
Drug delivery system
Extracellular vesicles
Inflammatory disease
Journal
Experimental neurobiology
ISSN: 1226-2560
Titre abrégé: Exp Neurobiol
Pays: Korea (South)
ID NLM: 101278187
Informations de publication
Date de publication:
28 Feb 2021
28 Feb 2021
Historique:
received:
07
12
2020
revised:
06
01
2021
accepted:
17
01
2021
entrez:
26
2
2021
pubmed:
27
2
2021
medline:
27
2
2021
Statut:
ppublish
Résumé
Immune system is essential for host homeostasis. Immune cells communicate with each other by binding to receptors or by releasing vesicles including chemokines and cytokines. Under healthy circumstances, immune cell-derived factors are critical for cellular growth, division and function, whereas under conditions such as ageing and inflammatory states, they can aggravate pathologies and cause disease. Cell-derived membranous extracellular vesicles mediate cell-to-cell communication and are implicated in various physiological and pathological processes involving ageing and age-related diseases. Extracellular vesicles are responsible for spreading detrimental factors to the surroundings and the propagation phase of inflammatory diseases. The regulation of extracellular vesicles is a putative target for treatment of inflammatory diseases. Moreover, their features are ideal for developing biomarkers and drug delivery systems modulated by bioengineering in inflammatory diseases. The present review summarizes the current understanding of extracellular vesicles in ageing and inflammatory diseases.
Identifiants
pubmed: 33632983
pii: en20059
doi: 10.5607/en20059
pmc: PMC7926047
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
32-47Références
Clin Microbiol Rev. 2009 Apr;22(2):240-73, Table of Contents
pubmed: 19366914
Nat Rev Drug Discov. 2003 Jun;2(6):473-88
pubmed: 12776222
Ann Neurol. 2012 Oct;72(4):610-24
pubmed: 23109155
PLoS One. 2013 Jul 23;8(7):e69547
pubmed: 23936042
Front Immunol. 2014 Oct 07;5:491
pubmed: 25339958
Cell Death Differ. 2019 Mar;26(4):715-727
pubmed: 30737475
PLoS One. 2015 Sep 11;10(9):e0135858
pubmed: 26360050
FASEB J. 2005 Aug;19(10):1329-31
pubmed: 15919760
Clin Exp Immunol. 1994 Jul;97(1):26-32
pubmed: 8033415
Stroke. 2017 Aug;48(8):2292-2296
pubmed: 28536169
J Gerontol A Biol Sci Med Sci. 1998 Jan;53(1):M20-6
pubmed: 9467429
Brain Behav Immun. 2009 Mar;23(3):309-17
pubmed: 18814846
Nat Rev Gastroenterol Hepatol. 2019 Mar;16(3):185-196
pubmed: 30478416
Annu Rev Pathol. 2010;5:99-118
pubmed: 20078217
Nat Cell Biol. 2010 Jan;12(1):19-30; sup pp 1-13
pubmed: 19966785
J Immunol. 2011 Jun 1;186(11):6313-8
pubmed: 21531892
Nat Rev Immunol. 2002 Aug;2(8):569-79
pubmed: 12154376
Front Immunol. 2020 May 29;11:1040
pubmed: 32547552
Sci Rep. 2016 Nov 29;6:37975
pubmed: 27897233
Lancet. 2014 Jan 4;383(9911):69-82
pubmed: 23890997
Lancet. 2019 Jun 8;393(10188):2344-2358
pubmed: 31180031
Nat Rev Immunol. 2014 Mar;14(3):195-208
pubmed: 24566916
Cell. 2001 Oct 5;107(1):55-65
pubmed: 11595185
Clin Exp Rheumatol. 2012 Mar-Apr;30(2):262-5
pubmed: 22325161
Annu Rev Immunol. 2012;30:221-41
pubmed: 22224776
Lancet. 2014 Nov 22;384(9957):1878-1888
pubmed: 24881804
N Engl J Med. 2011 Dec 1;365(22):2110-21
pubmed: 22129255
Acta Neuropathol. 2016 Oct;132(4):577-92
pubmed: 27221146
Cell Mol Life Sci. 2013 Jan;70(2):181-203
pubmed: 22729185
J Lipid Res. 2018 Dec;59(12):2255-2261
pubmed: 29678958
Nat Rev Immunol. 2020 Feb;20(2):95-112
pubmed: 31558839
Nat Commun. 2013;4:2712
pubmed: 24231649
J Immunol. 2005 May 15;174(10):6440-8
pubmed: 15879146
Nat Rev Immunol. 2007 Jun;7(6):429-42
pubmed: 17525752
Cancer Res. 2006 May 1;66(9):4795-801
pubmed: 16651434
Methods Mol Biol. 2017;1554:193-200
pubmed: 28185192
J Exp Med. 2012 Jan 16;209(1):51-60
pubmed: 22213807
Cell. 2010 Mar 19;140(6):805-20
pubmed: 20303872
Curr Biol. 2009 Dec 1;19(22):1875-85
pubmed: 19896381
Front Immunol. 2019 Jul 17;10:1667
pubmed: 31379858
Biochim Biophys Acta. 2009 Dec;1793(12):1901-16
pubmed: 19781582
Cytokine. 2020 Sep;133:154481
pubmed: 30031680
J Immunol. 1999 Aug 1;163(3):1274-81
pubmed: 10415024
Biophys J. 2012 May 2;102(9):2031-8
pubmed: 22824266
Science. 2008 Feb 29;319(5867):1244-7
pubmed: 18309083
Nat Rev Immunol. 2013 Mar;13(3):159-75
pubmed: 23435331
Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):103-9
pubmed: 22034510
J Immunol. 1990 May 1;144(9):3347-53
pubmed: 2109776
Cell Res. 2012 Mar;22(3):607-10
pubmed: 22157651
Traffic. 2015 Jan;16(1):35-47
pubmed: 25284293
Exp Neurobiol. 2016 Oct;25(5):262-268
pubmed: 27790060
Neuroimmunomodulation. 2018;25(1):18-22
pubmed: 30021215
Cytokine Growth Factor Rev. 2020 Feb;51:49-60
pubmed: 31874738
Cell Death Dis. 2020 Oct 28;11(10):924
pubmed: 33116121
Oncogene. 2013 Oct 24;32(43):5129-43
pubmed: 23416979
Exp Neurobiol. 2019 Dec 31;28(6):643-657
pubmed: 31902153
Nat Rev Immunol. 2014 Mar;14(3):166-80
pubmed: 24481336
Cell Mol Neurobiol. 2018 Nov;38(8):1539-1550
pubmed: 30288631
Nat Immunol. 2015 Apr;16(4):343-53
pubmed: 25789684
NPJ Aging Mech Dis. 2016;2:
pubmed: 27928512
Nat Biotechnol. 2011 Apr;29(4):341-5
pubmed: 21423189
Immunology. 2003 Jun;109(2):246-54
pubmed: 12757620
BMC Immunol. 2010 Dec 13;11:61
pubmed: 21144017
J Lipid Res. 2018 Aug;59(8):1325-1340
pubmed: 29853528
Clin Microbiol Rev. 2002 Apr;15(2):294-309
pubmed: 11932234
PLoS Biol. 2020 Jan 16;18(1):e3000599
pubmed: 31945054
EMBO J. 2007 Oct 3;26(19):4263-72
pubmed: 17805347
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5437-42
pubmed: 12702770
J Immunol. 2002 Apr 1;168(7):3235-41
pubmed: 11907077
Cells. 2020 Apr 01;9(4):
pubmed: 32244730
J Biol Chem. 2009 Nov 6;284(45):31291-302
pubmed: 19758999
Blood. 2005 Sep 1;106(5):1604-11
pubmed: 15741221
Cell. 2016 Mar 10;164(6):1226-1232
pubmed: 26967288
Int J Mol Sci. 2016 Aug 26;17(9):
pubmed: 27571072
J Clin Invest. 2016 Apr 1;126(4):1173-80
pubmed: 27035808
Cell. 2003 Nov 14;115(4):377-88
pubmed: 14622593
Gerontology. 1993;39(1):7-18
pubmed: 8440492
Nat Commun. 2013;4:2980
pubmed: 24356509
Stem Cell Investig. 2017 Dec 19;4:98
pubmed: 29359137
Nature. 2014 May 22;509(7501):439-46
pubmed: 24848057
Sci Rep. 2018 Jul 3;8(1):9987
pubmed: 29968812
J Biomed Sci. 2019 Sep 1;26(1):64
pubmed: 31472685
Mol Neurobiol. 2019 Dec;56(12):8157-8167
pubmed: 31197655
N Engl J Med. 2008 Feb 28;358(9):929-39
pubmed: 18305268
Lancet. 2016 Oct 22;388(10055):2023-2038
pubmed: 27156434
Cell Mol Immunol. 2020 Apr;17(4):323-334
pubmed: 32203193
J Exp Med. 2004 Sep 20;200(6):749-59
pubmed: 15365096
Inflamm Bowel Dis. 2016 Jul;22(7):1587-95
pubmed: 27271497
PLoS Pathog. 2014 Jun 12;10(6):e1004176
pubmed: 24945624
PLoS One. 2018 Apr 24;13(4):e0195969
pubmed: 29689087
Lancet. 2010 Sep 25;376(9746):1094-108
pubmed: 20870100
Mol Neurobiol. 2018 Jul;55(7):6112-6128
pubmed: 29188495
Nat Rev Mol Cell Biol. 2010 Aug;11(8):556-66
pubmed: 20588296
Diabetes. 2017 Feb;66(2):460-473
pubmed: 27872147
Arthritis Rheum. 2002 Nov;46(11):2857-66
pubmed: 12428225
N Engl J Med. 2009 Nov 19;361(21):2066-78
pubmed: 19923578
J Immunol. 2013 Apr 1;190(7):3346-53
pubmed: 23427247
Nat Rev Mol Cell Biol. 2018 Apr;19(4):213-228
pubmed: 29339798
Elife. 2016 Aug 25;5:
pubmed: 27559612
Nature. 2010 Apr 8;464(7290):864-9
pubmed: 20305637
J Cell Sci. 2013 Dec 15;126(Pt 24):5553-65
pubmed: 24105262
Nat Rev Rheumatol. 2014 Jun;10(6):356-64
pubmed: 24535546
Genome Biol. 2001;2(5):REVIEWS3007
pubmed: 11387043
J Virol. 2009 Jan;83(2):512-21
pubmed: 18987139
Nat Rev Neurol. 2016 Jun;12(6):346-57
pubmed: 27174238
Arthritis Rheum. 2013 Oct;65(10):2680-90
pubmed: 23817959
Cell. 2019 Apr 18;177(3):524-540
pubmed: 31002794
Cell Mol Life Sci. 2018 Jan;75(2):193-208
pubmed: 28733901
J Vis Exp. 2016 Jan 05;(107):
pubmed: 26780239
FEBS J. 2009 Apr;276(8):2201-12
pubmed: 19302216
Lancet. 2018 Jun 16;391(10138):2449-2462
pubmed: 29916386
Intest Res. 2018 Jan;16(1):26-42
pubmed: 29422795
Cell. 2004 Jan 23;116(2):153-66
pubmed: 14744428
Mediators Inflamm. 2014;2014:826987
pubmed: 24729663
Sci Rep. 2018 Jun 12;8(1):8973
pubmed: 29895824
Allergy Asthma Clin Immunol. 2018 Sep 12;14(Suppl 2):49
pubmed: 30263032
F1000Res. 2018 Sep 26;7:
pubmed: 30345015
Diabetes. 2014 Mar;63(3):1008-20
pubmed: 24170696
Acta Pharm Sin B. 2016 Jul;6(4):287-96
pubmed: 27471669
Cytokine. 2014 Feb;65(2):126-9
pubmed: 24355430
J Cell Sci. 2010 May 15;123(Pt 10):1603-11
pubmed: 20445011
Sci Rep. 2018 May 8;8(1):7227
pubmed: 29740045
J Clin Med. 2017 Jul 10;6(7):
pubmed: 28698517
J Allergy Clin Immunol. 2010 Feb;125(2 Suppl 2):S33-40
pubmed: 20061006
J Immunol Res. 2018 Jun 11;2018:1467538
pubmed: 29992170
Cell Death Dis. 2018 Feb 15;9(3):266
pubmed: 29449647
Lancet. 2016 Mar 19;387(10024):1211-26
pubmed: 26377143
J Extracell Vesicles. 2015 May 14;4:27066
pubmed: 25979354
Curr Opin Cell Biol. 2000 Aug;12(4):503-8
pubmed: 10873823
J Exp Med. 2000 Oct 2;192(7):977-86
pubmed: 11015439
Front Immunol. 2018 Jun 28;9:1486
pubmed: 30002658
Small GTPases. 2017 Oct 2;8(4):220-232
pubmed: 27494381
Cell. 2015 Feb 26;160(5):816-827
pubmed: 25723161
J Biol Chem. 2013 Apr 26;288(17):11649-61
pubmed: 23463506
Nat Med. 1997 Feb;3(2):189-95
pubmed: 9018238
Arthritis Rheum. 2009 Feb;60(2):380-9
pubmed: 19180475
Arthritis Res Ther. 2016 Nov 16;18(1):264
pubmed: 27852323
Immun Ageing. 2020 Jan 20;17:2
pubmed: 31988649
Clin Exp Immunol. 2009 Feb;155(2):173-81
pubmed: 19128359
Annu Rev Immunol. 2012;30:459-89
pubmed: 22224774
Nat Commun. 2019 Mar 8;10(1):1144
pubmed: 30850633
Nat Commun. 2017 Feb 17;8:14448
pubmed: 28211508
Ther Deliv. 2011 Sep;2(9):1095-9
pubmed: 22833906
Semin Immunol. 2018 Dec;40:101275
pubmed: 31088710
Immunol Rev. 2012 May;247(1):160-71
pubmed: 22500839
Immunol Rev. 2013 Jul;254(1):78-101
pubmed: 23772616
Lab Invest. 2000 May;80(5):617-53
pubmed: 10830774
Cell Signal. 2020 Nov;75:109771
pubmed: 32896608
Nature. 2015 Jul 9;523(7559):177-82
pubmed: 26106858
J Crohns Colitis. 2016 Feb;10(2):186-93
pubmed: 26507860
Aging Cell. 2018 Apr;17(2):
pubmed: 29392820
Curr Opin Cell Biol. 2009 Aug;21(4):575-81
pubmed: 19442504
Nat Rev Immunol. 2017 Jan;17(1):30-48
pubmed: 27890914
Sci Rep. 2017 Jul 6;7(1):4776
pubmed: 28684770
Nat Rev Immunol. 2018 Jun;18(6):363-373
pubmed: 29520044
Annu Rev Immunol. 2000;18:767-811
pubmed: 10837075
Cold Spring Harb Perspect Med. 2012 May;2(5):a006940
pubmed: 22553496
Brain. 2016 Feb;139(Pt 2):481-94
pubmed: 26647156
Semin Cancer Biol. 2014 Oct;28:3-13
pubmed: 24769058
J Allergy Clin Immunol. 2010 Feb;125(2 Suppl 2):S3-23
pubmed: 20176265
Cell Immunol. 1998 Sep 15;188(2):105-10
pubmed: 9756640
Immunity. 2018 Feb 20;48(2):202-213
pubmed: 29466753
J Autoimmun. 2020 Jun;110:102392
pubmed: 31911013
Diabetes. 2011 Aug;60(8):2112-9
pubmed: 21659501
Sci Transl Med. 2015 Nov 25;7(315):315ra190
pubmed: 26606969
Proc Natl Acad Sci U S A. 1986 Nov;83(22):8749-53
pubmed: 3490671
Lancet Gastroenterol Hepatol. 2020 Jan;5(1):17-30
pubmed: 31648971
AIDS Res Hum Retroviruses. 2011 Feb;27(2):167-78
pubmed: 20964480
J Immunol Res. 2014;2014:385352
pubmed: 25436214
Rheumatology (Oxford). 2001 Jun;40(6):662-7
pubmed: 11426024
Arthritis Rheumatol. 2016 Feb;68(2):462-72
pubmed: 26360137
Arthritis Rheum. 1990 May;33(5):634-43
pubmed: 2346519
EMBO Mol Med. 2013 Feb;5(2):235-49
pubmed: 23165896
Retrovirology. 2004 Mar 08;1:2
pubmed: 15169555
Nat Immunol. 2016 Jan;17(1):9-17
pubmed: 26681457
Eur J Immunol. 2013 Dec;43(12):3279-90
pubmed: 23943377
Proteomics. 2019 Apr;19(8):e1800149
pubmed: 30758141
J Immunol. 1998 Apr 1;160(7):3513-21
pubmed: 9531313
Acta Pharmacol Sin. 2009 Oct;30(10):1454-61
pubmed: 19749786
Cancers (Basel). 2016 Mar 15;8(3):
pubmed: 26999211
Inflamm Res. 2014 Nov;63(11):943-50
pubmed: 25129403
Cells. 2018 Aug 18;7(8):
pubmed: 30126173
Lancet. 2014 Jul 19;384(9939):258-71
pubmed: 24907868
Aging Cell. 2020 Mar;19(3):e13103
pubmed: 31960578
Cent Eur J Immunol. 2017;42(4):390-398
pubmed: 29472818
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11172-7
pubmed: 16837572
Immun Ageing. 2008 Jul 16;5:5
pubmed: 18631391
Cell Death Differ. 2008 Nov;15(11):1723-33
pubmed: 18617898