Human Dental Pulp Stem Cells Modulate Cytokine Production
COVID-19
SARS-CoV-2
cytokine
dental pulp stem cells
immunomodulation
interleukin
mesenchymal stem cells
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
09
2020
accepted:
23
12
2020
entrez:
26
2
2021
pubmed:
27
2
2021
medline:
27
2
2021
Statut:
epublish
Résumé
A subset of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) developed a condition of hyper-inflammation, which can cause multi-organ damage and the more severe forms of coronavirus disease 2019 (COVID-19). Mesenchymal stem cells (MSCs) can promote tissue regeneration and modulate immune responses and, thus, have the rational requirements to be used to counteract SARS-CoV-2-induced pneumonia and hyper-inflammation. The aim of the present study was to gain insight into possible mechanisms of action of MSCs obtained from human dental pulp [dental pulp stem cells (DPSCs)] in COVID-19 patients. We investigated the concentrations of 18 cytokines in supernatants of peripheral blood mononuclear cells (PBMCs) obtained from COVID-19 patients cultured
Identifiants
pubmed: 33634100
doi: 10.3389/fcell.2020.609204
pmc: PMC7901970
doi:
Types de publication
Journal Article
Langues
eng
Pagination
609204Informations de copyright
Copyright © 2021 Croci, Bonacini, Dolci, Massari, Facciolongo, Pignatti, Pisciotta, Carnevale, Negro, Cassone, Muratore, Belloni, Zerbini and Salvarani.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Crit Care Explor. 2020 Jun 22;2(6):e0144
pubmed: 32696007
Nat Commun. 2020 Jul 6;11(1):3434
pubmed: 32632085
Transplantation. 2005 Sep 27;80(6):836-42
pubmed: 16210973
Int Immunopharmacol. 2017 Jun;47:59-69
pubmed: 28364628
Aging Dis. 2020 Mar 9;11(2):216-228
pubmed: 32257537
Life Sci. 2020 Oct 1;258:118167
pubmed: 32735885
Curr Opin Rheumatol. 2017 Mar;29(2):201-207
pubmed: 27941390
Nat Commun. 2018 Dec 21;9(1):5457
pubmed: 30575716
Stem Cell Res Ther. 2020 Aug 18;11(1):361
pubmed: 32811531
Nat Rev Immunol. 2020 Aug;20(8):507-514
pubmed: 32576980
J Dent Res. 2002 Aug;81(8):531-5
pubmed: 12147742
Stem Cells Dev. 2018 Sep 1;27(17):1191-1202
pubmed: 29978730
Drugs. 2020 Sep;80(13):1267-1292
pubmed: 32696108
Signal Transduct Target Ther. 2020 Aug 27;5(1):172
pubmed: 32855385
Front Cell Dev Biol. 2020 May 15;8:279
pubmed: 32500073
Cytotherapy. 2011 Nov;13(10):1205-20
pubmed: 21905956
Cell Immunol. 2016 Dec;310:108-115
pubmed: 27576175
Cytokine Growth Factor Rev. 2015 Oct;26(5):475-87
pubmed: 26189695
Cleve Clin J Med. 2020 Jun 30;87(7):389-393
pubmed: 32393592
Cell Prolif. 2020 Jan;53(1):e12712
pubmed: 31730279
Cell Immunol. 2016 Apr;302:26-31
pubmed: 26774852
Stem Cell Res Ther. 2020 May 4;11(1):169
pubmed: 32366290
Expert Opin Biol Ther. 2020 Jul;20(7):711-716
pubmed: 32329380
Eur J Cell Biol. 2019 Dec;98(5-8):151041
pubmed: 31023504
Trials. 2020 Jun 12;21(1):520
pubmed: 32532356
J Leukoc Biol. 2020 Jul;108(1):17-41
pubmed: 32534467
Front Immunol. 2020 Jul 03;11:1563
pubmed: 32719683
J Endod. 2019 Nov;45(11):1342-1348
pubmed: 31540748
Circ Res. 2018 Aug 31;123(6):700-715
pubmed: 29970365
Medicine (Baltimore). 2020 Jul 31;99(31):e21429
pubmed: 32756149
Cytometry A. 2020 Jul;97(7):668-673
pubmed: 32275124
Stem Cells Dev. 2020 Jun 15;29(12):747-754
pubmed: 32380908
Cell Transplant. 2020 Jan-Dec;29:963689720952089
pubmed: 32830527
Front Med. 2020 Oct;14(5):664-673
pubmed: 32761491
Lancet Rheumatol. 2020 Aug;2(8):e474-e484
pubmed: 32835257
Ann Rheum Dis. 2010 Jan;69(1):241-8
pubmed: 19124525
Int Immunopharmacol. 2019 Sep;74:105687
pubmed: 31295689
Cytokine Growth Factor Rev. 2019 Jun;47:32-42
pubmed: 31129018
Stem Cell Res Ther. 2019 May 2;10(1):131
pubmed: 31046833
PLoS One. 2008 Apr 02;3(4):e1886
pubmed: 18382669
Cytotherapy. 2006;8(4):315-7
pubmed: 16923606
Arthritis Rheumatol. 2015 May;67(5):1250-60
pubmed: 25604648
Stem Cells Transl Med. 2013 Jun;2(6):455-63
pubmed: 23694810
Ann N Y Acad Sci. 2015 Sep;1351:114-26
pubmed: 26152292
J Transl Med. 2020 May 18;18(1):203
pubmed: 32423449
Mod Rheumatol. 2021 Jan;31(1):186-196
pubmed: 31859545
J Stem Cells Regen Med. 2017 Dec 18;13(2):62-74
pubmed: 29391751
Nature. 2020 Aug;584(7821):463-469
pubmed: 32717743
Crit Care. 2020 Jul 11;24(1):420
pubmed: 32653043
Pulmonology. 2021 Jan-Feb;27(1):52-66
pubmed: 32713784
Stem Cell Rev Rep. 2020 Jun;16(3):427-433
pubmed: 32281052
Dent J (Basel). 2018 Dec 13;6(4):
pubmed: 30551556
Stem Cell Res Ther. 2020 May 27;11(1):207
pubmed: 32460839
Nat Rev Immunol. 2020 Jun;20(6):363-374
pubmed: 32346093
Cytokine Growth Factor Rev. 2020 Aug;54:62-75
pubmed: 32513566
Neural Regen Res. 2020 Mar;15(3):373-381
pubmed: 31571644
J Dent Res. 2012 Oct;91(10):948-54
pubmed: 22904205
J Infect Dis. 2020 Aug 4;222(5):746-754
pubmed: 32563194
World J Stem Cells. 2014 Nov 26;6(5):526-39
pubmed: 25426250
Ann Rheum Dis. 2018 Dec;77(12):1815-1824
pubmed: 30097452
Nat Med. 2020 Oct;26(10):1636-1643
pubmed: 32839624
BMC Dev Biol. 2015 Mar 14;15:14
pubmed: 25879198