Acute Flare of Adult-Onset Autoimmune Enteropathy Associated With Cyclophosphamide.


Journal

ACG case reports journal
ISSN: 2326-3253
Titre abrégé: ACG Case Rep J
Pays: United States
ID NLM: 101638398

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 25 03 2020
accepted: 04 10 2020
entrez: 26 2 2021
pubmed: 27 2 2021
medline: 27 2 2021
Statut: epublish

Résumé

This is a case of adult-onset autoimmune enteropathy (AIE) in a 46-year-old man with multiple autoimmune conditions who presented with worsening disease process after receiving cyclophosphamide. We describe the investigations and management of this patient over a 6-year timeline. The diagnosis and management of AIE is challenging given the heterogeneity in clinicopathologic findings and a small number of adult case reports. We describe the current diagnostic criteria, review the literature on treatment options and outcomes, and discuss the evidence for cyclophosphamide in the treatment of AIE. Adult-onset AIE should be considered in the differential diagnosis of refractory diarrhea and weight loss.

Identifiants

pubmed: 33634202
doi: 10.14309/crj.0000000000000541
pii: ACGCR-20-0274
pmc: PMC7901791
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e00541

Informations de copyright

© 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

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Auteurs

Jasmine Liu (J)

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Ziad Hindi (Z)

Department of Medicine, Schulich School of Medicine and Dentistry, London, Ontario.

Tariq Aziz (T)

Division of Anatomical Pathology, McMaster University, Hamilton, Ontario, Canada.

Siwar Albashir (S)

Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada.

Classifications MeSH