Discriminating transudates and exudates in dogs with pleural effusion: diagnostic utility of simplified Light's criteria compared with traditional veterinary classification.
canine
lactate dehydrogenase
light's criteria
pleural effusion
Journal
The Veterinary record
ISSN: 2042-7670
Titre abrégé: Vet Rec
Pays: England
ID NLM: 0031164
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
19
07
2019
revised:
11
11
2019
accepted:
31
12
2019
entrez:
27
2
2021
pubmed:
28
2
2021
medline:
21
4
2021
Statut:
ppublish
Résumé
To determine whether the simplified Light's criteria (ie, pleural effusion lactate dehydrogenase concentration and serum total protein) can identify the pathophysiology of pleural effusion formation in dogs, and to assess whether these criteria were more accurate than the traditional veterinary classification based on pleural effusion total protein (TPp) and nucleated cell count (TNCCp). This is a cross-sectional study including 100 dogs with pleural effusion. The aetiology of effusion was used to classify the pathophysiology of its formation. Parameters measured included the simplified Light's criteria, TPp and TNCCp. The diagnostic utility of the two methods in classifying pleural effusion formation was evaluated. Seven transudates due to decreased colloid osmotic pressure, 18 transudates due to increased hydrostatic pressure gradient and 75 exudates were included in the study. The simplified Light's criteria misclassified 2 of 75 exudates (98 per cent overall accuracy). The traditional veterinary classification scheme misclassified 31 of 75 exudates and 12 of 18 increased hydrostatic pressure gradient transudates (57 per cent overall accuracy). The frequency of agreement between the simplified Light's criteria and the traditional veterinary classification with the true nature of the pleural effusion was significantly different (P<0.001). The simplified Light's criteria were highly accurate in discriminating exudates from transudates, while TPp and TNCCp had no diagnostic value in doing so.
Substances chimiques
Blood Proteins
0
L-Lactate Dehydrogenase
EC 1.1.1.27
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e5Informations de copyright
© British Veterinary Association 2020.
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