Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE
Apolipoprotein E knockout (ApoE−/−) mice
Western-type diet
acute phase response
ischemic heart disease
recombinant human apolipoprotein serum amyloid A (hApo-SAA)
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
28
08
2020
revised:
16
11
2020
accepted:
10
12
2020
entrez:
27
2
2021
pubmed:
28
2
2021
medline:
27
7
2021
Statut:
ppublish
Résumé
Airway exposure to eg particulate matter is associated with cardiovascular disease including atherosclerosis. Acute phase genes, especially Serum Amyloid A3 (Saa3), are highly expressed in the lung following pulmonary exposure to particles. We aimed to investigate whether the human acute phase protein SAA (a homolog to mouse SAA3) accelerated atherosclerotic plaque progression in Apolipoprotein E knockout (ApoE
Identifiants
pubmed: 33638910
doi: 10.1096/fj.202002017R
doi:
Substances chimiques
Apolipoproteins E
0
Lipids
0
Serum Amyloid A Protein
0
Malondialdehyde
4Y8F71G49Q
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e21307Informations de copyright
© 2021 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology.
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