How to Test Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines Ethically Even After One Is Available.

COVID-19 vaccine ethics randomized controlled trials as topic

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
16 12 2021
Historique:
received: 14 12 2020
pubmed: 28 2 2021
medline: 24 12 2021
entrez: 27 2 2021
Statut: ppublish

Résumé

Although vaccines against severe acute respiratory syndrome coronavirus 2 have now been found safe and efficacious, there remains an urgent global health need to test both these vaccines and additional vaccines against the same virus. Under variable conditions, either standard or unusual designs would for both familiar and often-missed reasons make continued testing possible and ethical.

Identifiants

pubmed: 33639622
pii: 6152007
doi: 10.1093/cid/ciab182
pmc: PMC7989578
doi:

Substances chimiques

Vaccines 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2332-2334

Subventions

Organisme : NIH/NIAID
ID : AI114617-01A1
Organisme : Wellcome Trust
ID : 208766/Z/17/Z
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R01 AI114617
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R56 AI114617
Pays : United States
Organisme : National Science Foundation
ID : 2039320

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Références

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pubmed: 33273060
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pubmed: 32232474
JAMA. 2021 Jan 19;325(3):219-220
pubmed: 33315080
J Med Ethics. 2020 Jul;46(7):465-469
pubmed: 32414757
Lancet. 2020 Nov 21;396(10263):1611-1613
pubmed: 33125926
Vaccine. 2014 Aug 20;32(37):4708-12
pubmed: 24768580
Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28538-28542
pubmed: 33122444
Science. 2020 Oct 23;370(6515):389-390
pubmed: 33093087
Science. 2020 May 22;368(6493):832-834
pubmed: 32381590
N Engl J Med. 2020 Sep 3;383(10):e63
pubmed: 32610006
N Engl J Med. 2021 Jan 14;384(2):e2
pubmed: 33264543
Ann Intern Med. 2021 Feb;174(2):221-228
pubmed: 33090877
NPJ Vaccines. 2021 Apr 12;6(1):51
pubmed: 33846340
J Med Ethics. 2020 Dec;46(12):808-812
pubmed: 32661074

Auteurs

Nir Eyal (N)

Center for Population-Level Bioethics and Department of Philosophy, Rutgers University, New Brunswick, New Jersey, USA.
Department of Health Behavior, Society and Policy, Rutgers School of Public Health, Piscataway, New Jersey, USA.

Marc Lipsitch (M)

Center for Communicable Disease Dynamics, Department of Epidemiology, and Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.

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Classifications MeSH