Efficacy of parent-infant psychotherapy compared to care as usual in children with regulatory disorders in clinical and outpatient settings: study protocol of a randomised controlled trial as part of the SKKIPPI project.


Journal

BMC psychiatry
ISSN: 1471-244X
Titre abrégé: BMC Psychiatry
Pays: England
ID NLM: 100968559

Informations de publication

Date de publication:
27 02 2021
Historique:
received: 08 01 2021
accepted: 09 02 2021
entrez: 28 2 2021
pubmed: 1 3 2021
medline: 27 4 2021
Statut: epublish

Résumé

The first years of life are a significant period for child development, when children are particularly sensitive and prone to crises. This early phase lays the foundation for healthy growth. Clinical assessment of psychological symptoms in early infancy and adequate treatment are both important in improving the diagnostic outcome and preventing later long-term developmental consequences. The most common psychological problems in the first 3 years of life are regulatory disorders. The aim of this trial is to investigate the efficacy of Parent-Infant Psychotherapy (PIP) for infants and young children (aged 0-36 months, diagnosed with at least one regulatory disorder) and their mothers, compared to care as usual (CAU). In this open multicentre randomised controlled trial, 160 mother-infant dyads are randomised to receive PIP or CAU for 6 weeks of intervention in clinical or outpatient (including home treatment) settings. The primary outcome is the maternal sensitivity (sensitivity scale of the Emotional Availability Scales (EAS)) after 6 weeks. Secondary outcomes include assessment of interaction, mental health problems, attachment, development, psychological factors, treatment adherence, health care system utilisation, and costs, after 6 weeks and 12 months. This study will evaluate whether a manualised focus-based short-term psychodynamic psychotherapeutic intervention in mother-child dyads improves the care situation for families of children diagnosed with regulatory disorders, and helps prevent long-term psychopathologies. Assessment of the intervention in different settings will support the development of more tailored interventions for affected infants and their mothers. German Clinical Trial Register, ID: DRKS00017008 . Registered 03/20/2019.

Sections du résumé

BACKGROUND
The first years of life are a significant period for child development, when children are particularly sensitive and prone to crises. This early phase lays the foundation for healthy growth. Clinical assessment of psychological symptoms in early infancy and adequate treatment are both important in improving the diagnostic outcome and preventing later long-term developmental consequences. The most common psychological problems in the first 3 years of life are regulatory disorders. The aim of this trial is to investigate the efficacy of Parent-Infant Psychotherapy (PIP) for infants and young children (aged 0-36 months, diagnosed with at least one regulatory disorder) and their mothers, compared to care as usual (CAU).
METHODS
In this open multicentre randomised controlled trial, 160 mother-infant dyads are randomised to receive PIP or CAU for 6 weeks of intervention in clinical or outpatient (including home treatment) settings. The primary outcome is the maternal sensitivity (sensitivity scale of the Emotional Availability Scales (EAS)) after 6 weeks. Secondary outcomes include assessment of interaction, mental health problems, attachment, development, psychological factors, treatment adherence, health care system utilisation, and costs, after 6 weeks and 12 months.
DISCUSSION
This study will evaluate whether a manualised focus-based short-term psychodynamic psychotherapeutic intervention in mother-child dyads improves the care situation for families of children diagnosed with regulatory disorders, and helps prevent long-term psychopathologies. Assessment of the intervention in different settings will support the development of more tailored interventions for affected infants and their mothers.
TRIAL REGISTRATION
German Clinical Trial Register, ID: DRKS00017008 . Registered 03/20/2019.

Identifiants

pubmed: 33639894
doi: 10.1186/s12888-021-03112-6
pii: 10.1186/s12888-021-03112-6
pmc: PMC7913440
doi:

Types de publication

Clinical Trial Protocol Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

118

Subventions

Organisme : Innovationsfond/GBA Germany
ID : 01 VSF17027

Références

Cochrane Database Syst Rev. 2015 Jan 08;1:CD010534
pubmed: 25569177
Br J Psychiatry Suppl. 1998;(34):10-7
pubmed: 9829011
Trials. 2020 Jun 5;21(1):490
pubmed: 32503611
J Am Acad Child Psychiatry. 1975 Summer;14(3):387-421
pubmed: 1141566
Infancy. 2002 Apr;3(2):133-152
pubmed: 33451205
PLoS One. 2017 May 4;12(5):e0176218
pubmed: 28472162
Br J Psychiatry. 1987 Jun;150:782-6
pubmed: 3651732
Br J Psychiatry. 2003 May;182:420-7
pubmed: 12724245
Soc Psychiatry Psychiatr Epidemiol. 2021 Jun;56(6):1103-1112
pubmed: 33337512
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Dec;63(12):1538-1547
pubmed: 33146761
Child Dev. 1991 Feb;62(1):199-209
pubmed: 2022136
J Am Acad Child Adolesc Psychiatry. 2021 Jun;60(6):723-733
pubmed: 32976954
Attach Hum Dev. 2013;15(4):349-67
pubmed: 23550526
J Health Organ Manag. 2020 Oct 14;34(8):915-923
pubmed: 33063505
Infant Ment Health J. 2016 Mar-Apr;37(2):97-114
pubmed: 26939716
Infant Ment Health J. 2015 Jul-Aug;36(4):366-87
pubmed: 26112776
Arch Dis Child. 2011 Jul;96(7):622-9
pubmed: 21508059
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Feb;62(2):195-204
pubmed: 30627734
J Consult Clin Psychol. 1991 Feb;59(1):12-9
pubmed: 2002127
Infant Ment Health J. 2011 May;32(3):377-404
pubmed: 26904966
Psychol Bull. 2003 Mar;129(2):195-215
pubmed: 12696839
Eur Psychiatry. 2015 Jul;30(5):583-9
pubmed: 25735811
J Affect Disord. 2020 Jan 1;260:670-679
pubmed: 31550613
Dev Psychopathol. 2006 Summer;18(3):623-49
pubmed: 17152394
Eur Child Adolesc Psychiatry. 2001;10 Suppl 1:I71-9
pubmed: 11794558

Auteurs

Mona Katharina Sprengeler (MK)

Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany. mona.sprengeler@medizin.uni-leipzig.de.

Janna Mattheß (J)

International Psychoanalytic University Berlin, Berlin, Germany.

Melanie Eckert (M)

International Psychoanalytic University Berlin, Berlin, Germany.

Katharina Richter (K)

International Psychoanalytic University Berlin, Berlin, Germany.
Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Gabriele Koch (G)

International Psychoanalytic University Berlin, Berlin, Germany.

Thomas Reinhold (T)

Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Petra Vienhues (P)

Fachklinik für Psychiatrie, Psychosomatik und Psychotherapie, DIAKO Nordfriesland, Flensburg, Germany.

Anne Berghöfer (A)

Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Julia Fricke (J)

Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Stephanie Roll (S)

Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Thomas Keil (T)

Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Institute for Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
State Institute of Health, Bavarian Health and Food Safety Authority, Bad Kissingen, Germany.

Christiane Ludwig-Körner (C)

International Psychoanalytic University Berlin, Berlin, Germany.

Lars Kuchinke (L)

Psychological Methods and Evaluation, International Psychoanalytic University Berlin, Berlin, Germany.

Kai von Klitzing (K)

Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.

Franziska Schlensog-Schuster (F)

Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH