Detection of EGFR Activating and Resistance Mutations by Droplet Digital PCR in Sputum of EGFR-Mutated NSCLC Patients.

BACKGROUND

Proof of the T790M resistance mutation is mandatory if patients with

METHODS

Twenty-eight patients with advanced

RESULTS

Activating

CONCLUSIONS

We demonstrated that

Informations de copyright

© The Author(s) 2021.

Déclaration de conflit d'intérêts

Declaration of conflicting interests:The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: K.H. has received honoraria from AstraZeneca and Roche. A.B. has received honoraria from AstraZeneca. M.J.H. has received honoraria from AstraZeneca, Bristol Myers Squibb, Boehringer Ingelheim, Merck Sharp & Dohme, Pfizer, and Roche and had consulting or advisory roles with Boehringer Ingelheim, Merck Sharp & Dohme, Novartis, and Roche. O.C.B. has received honoraria from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Menarini, Novartis, Roche, and Takeda. P.E. has received honoraria from AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Menarini, Merck Sharp & Dohme, Novartis, and Roche and had consulting or advisory roles with Boehringer Ingelheim, Bristol Myers Squibb, Chiesi, Menarini, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and Takeda. M.F. has received honoraria from AstraZeneca, Bayer, Biomedica, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme, Myriad Genetics Inc, Pfizer, and Roche. H.F., C.G., and M.S. declare that they have no conflicts of interest that might be relevant to the contents of this article.