Alteration of Gut Microbiota After Antibiotic Exposure in Finishing Swine.

antimicrobial fecal microbiome gut dysfunction meta-analysis swine

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2021
Historique:
received: 18 08 2020
accepted: 21 01 2021
entrez: 1 3 2021
pubmed: 2 3 2021
medline: 2 3 2021
Statut: epublish

Résumé

Subclinical doses of antimicrobials are commonly used in the swine industry to control infectious diseases and growth performance. Accumulating evidence suggests that swine administered with antibiotics are susceptible to disease development due to disruption of the beneficial gut microbial community, which is associated with host immune regulation, nutrient digestion, and colonization resistance against pathogens. In this study, we found that finishing swine administered with lincomycin showed gut dysbiosis and increased diarrhea incidence compared with control swine. 16S rRNA amplicon sequencing was used to analyze the gut microbiota in finishing swine administered with lincomycin. The relative abundance of detrimental microbes, such as species of

Identifiants

pubmed: 33643231
doi: 10.3389/fmicb.2021.596002
pmc: PMC7906994
doi:

Types de publication

Journal Article

Langues

eng

Pagination

596002

Informations de copyright

Copyright © 2021 Jo, Kwon, Whon, Kim, Yun, Lee, Shin, Kim and Choi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15485-90
pubmed: 22955886
Anim Biotechnol. 2002 May;13(1):7-27
pubmed: 12212945
Appl Microbiol Biotechnol. 2018 Mar;102(5):2289-2299
pubmed: 29362824
Front Microbiol. 2014 Nov 04;5:580
pubmed: 25408688
Int J Biol Macromol. 2017 Dec;105(Pt 3):1622-1629
pubmed: 28219687
Vet Microbiol. 2017 Aug;207:149-152
pubmed: 28757016
Gastroenterology. 2014 May;146(6):1525-33
pubmed: 24560870
Genome Biol. 2011 Jun 24;12(6):R60
pubmed: 21702898
Clin Microbiol Infect. 2016 Jan;22(1):22-27
pubmed: 26454061
J Microbiol Biotechnol. 2015 Apr;25(4):431-8
pubmed: 25370726
Nucleic Acids Res. 2002 Jul 15;30(14):3059-66
pubmed: 12136088
Trends Mol Med. 2016 Jun;22(6):458-478
pubmed: 27178527
Science. 2005 Mar 25;307(5717):1920-5
pubmed: 15790845
Glycobiology. 2009 Jul;19(7):715-25
pubmed: 19282391
Prostaglandins Other Lipid Mediat. 2005 Sep;77(1-4):131-40
pubmed: 16099398
Front Microbiol. 2019 May 15;10:1035
pubmed: 31156580
Nat Methods. 2016 Jul;13(7):581-3
pubmed: 27214047
Antimicrob Agents Chemother. 2017 Oct 24;61(11):
pubmed: 28848008
Int J Syst Evol Microbiol. 2007 Jun;57(Pt 6):1291-1294
pubmed: 17551045
Sci Rep. 2015 Apr 21;5:9938
pubmed: 25898122
Front Microbiol. 2018 Nov 06;9:2707
pubmed: 30459747
Trends Microbiol. 2002 Jun;10(6):254-7
pubmed: 12088651
Bioinformatics. 2014 Nov 1;30(21):3123-4
pubmed: 25061070
J Biol Chem. 1990 Aug 15;265(23):13490-7
pubmed: 2166030
Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6
pubmed: 23193283
Cell. 2018 Mar 8;172(6):1198-1215
pubmed: 29522742
Nat Rev Microbiol. 2013 Apr;11(4):277-84
pubmed: 23474681
J Anim Sci Biotechnol. 2014 Mar 01;5(1):15
pubmed: 24580966
Scand J Gastroenterol. 1997 Sep;32(9):920-4
pubmed: 9299672
Trends Microbiol. 2017 Oct;25(10):851-873
pubmed: 28602521
Front Microbiol. 2013 Dec 03;4:364
pubmed: 24348472
Front Vet Sci. 2019 Mar 04;6:48
pubmed: 30886850
BMC Vet Res. 2019 May 24;15(1):172
pubmed: 31126262
Structure. 2009 Dec 9;17(12):1649-1659
pubmed: 20004168
Cell. 2016 Nov 17;167(5):1339-1353.e21
pubmed: 27863247
PLoS One. 2010 Mar 10;5(3):e9490
pubmed: 20224823
J Biol Chem. 1946 Oct;165(2):437-41
pubmed: 20276107
J Clin Microbiol. 2004 Mar;42(3):1203-6
pubmed: 15004076
Amino Acids. 2018 Nov;50(11):1497-1510
pubmed: 30116978
Proc Natl Acad Sci U S A. 2015 May 5;112(18):5649-54
pubmed: 25792457
J Nutr. 2014 Feb;144(2):218-23
pubmed: 24259555
Microbiome. 2018 May 17;6(1):90
pubmed: 29773078
Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1691-6
pubmed: 22307632
Nat Biotechnol. 2013 Sep;31(9):814-21
pubmed: 23975157
Front Microbiol. 2014 Jun 10;5:276
pubmed: 24959163
Int J Syst Evol Microbiol. 2003 Nov;53(Pt 6):2027-31
pubmed: 14657140
Sci Rep. 2019 Sep 9;9(1):12918
pubmed: 31501492
Anaerobe. 2004 Feb;10(1):47-50
pubmed: 16701500
Antonie Van Leeuwenhoek. 2018 Sep;111(9):1673-1685
pubmed: 29497869
Cell Host Microbe. 2018 Jun 13;23(6):705-715
pubmed: 29902436
Nat Microbiol. 2016 Sep 19;1:16161
pubmed: 27643971
Microbiome. 2020 Aug 4;8(1):114
pubmed: 32753050
Sci Rep. 2018 Apr 16;8(1):6012
pubmed: 29662088
Nature. 2013 Oct 3;502(7469):96-9
pubmed: 23995682
Aust Vet J. 1985 Aug;62(8):276-9
pubmed: 2865949

Auteurs

Hee Eun Jo (HE)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.
Department of Animal Science and Biotechnology, Chonnam National University, Gwangju, South Korea.

Min-Sung Kwon (MS)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.

Tae Woong Whon (TW)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.

Doo Wan Kim (DW)

Swine Division, National Institute of Animal Science, Rural Development Administration, Cheonan, South Korea.

Misun Yun (M)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.

Jieun Lee (J)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.

Mi-Young Shin (MY)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.
Department of Animal Science and Bioindustry, Chonnam National University, Gwangju, South Korea.

Sung-Hak Kim (SH)

Department of Animal Science and Biotechnology, Chonnam National University, Gwangju, South Korea.

Hak-Jong Choi (HJ)

Microbiology and Functionality Research Group, World Institute of Kimchi, Gwangju, South Korea.

Classifications MeSH