The effect of timing of initiation of renal replacement therapy on mortality: A retrospective case-control study.
Acute kidney injury
creatinine
propensity matching
renal replacement therapy
Journal
Journal of the Intensive Care Society
ISSN: 1751-1437
Titre abrégé: J Intensive Care Soc
Pays: England
ID NLM: 101538668
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
entrez:
1
3
2021
pubmed:
2
3
2021
medline:
2
3
2021
Statut:
ppublish
Résumé
To determine if earlier initiation of renal replacement therapy (RRT) is associated with improved survival in patients with severe acute kidney injury. We performed a retrospective case-control study of propensity-matched groups with multivariable logistic regression using Akaike Information Criteria to adjust for non-matched variables in a surgical ICU in a tertiary care hospital. We matched 169 of 205 (82%) patients with new initiation of RRT (EARLY group) to 169 similar patients who did not initiate RRT on that day (DEFERRED group). Eighteen (11%) of DEFERRED eventually received RRT before discharge. By univariate analysis, ICU mortality was higher in EARLY (n = 60 (36%) vs. n = 23 (14%), While ICU mortality was increased in the EARLY group, there was no difference in hospital mortality between EARLY and DEFERRED groups.
Identifiants
pubmed: 33643427
doi: 10.1177/1751143719892792
pii: 10.1177_1751143719892792
pmc: PMC7890751
doi:
Types de publication
Journal Article
Langues
eng
Pagination
8-16Subventions
Organisme : NCRR NIH HHS
ID : KL2 RR024987
Pays : United States
Informations de copyright
© The Intensive Care Society 2019.
Déclaration de conflit d'intérêts
Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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