Early Detection of Sepsis With Machine Learning Techniques: A Brief Clinical Perspective.
artificial intelligence
early diagnosis
machine learning
sepsis
supervised learning
unsupervised learning
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
10
2020
accepted:
19
01
2021
entrez:
1
3
2021
pubmed:
2
3
2021
medline:
2
3
2021
Statut:
epublish
Résumé
Sepsis is a major cause of death worldwide. Over the past years, prediction of clinically relevant events through machine learning models has gained particular attention. In the present perspective, we provide a brief, clinician-oriented vision on the following relevant aspects concerning the use of machine learning predictive models for the early detection of sepsis in the daily practice: (i) the controversy of sepsis definition and its influence on the development of prediction models; (ii) the choice and availability of input features; (iii) the measure of the model performance, the output, and their usefulness in the clinical practice. The increasing involvement of artificial intelligence and machine learning in health care cannot be disregarded, despite important pitfalls that should be always carefully taken into consideration. In the long run, a rigorous multidisciplinary approach to enrich our understanding in the application of machine learning techniques for the early recognition of sepsis may show potential to augment medical decision-making when facing this heterogeneous and complex syndrome.
Identifiants
pubmed: 33644097
doi: 10.3389/fmed.2021.617486
pmc: PMC7906970
doi:
Types de publication
Journal Article
Langues
eng
Pagination
617486Informations de copyright
Copyright © 2021 Giacobbe, Signori, Del Puente, Mora, Carmisciano, Briano, Vena, Ball, Robba, Pelosi, Giacomini and Bassetti.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Pediatr Crit Care Med. 2018 Oct;19(10):e495-e503
pubmed: 30052552
Ann Emerg Med. 2019 Apr;73(4):334-344
pubmed: 30661855
Diagnostics (Basel). 2019 Feb 13;9(1):
pubmed: 30781800
Front Pediatr. 2019 Oct 11;7:413
pubmed: 31681711
Pediatr Crit Care Med. 2005 Jan;6(1):2-8
pubmed: 15636651
Comput Methods Programs Biomed. 2019 Mar;170:1-9
pubmed: 30712598
Artif Intell Med. 2019 Sep;100:101725
pubmed: 31607345
Clin Microbiol Infect. 2020 May;26(5):584-595
pubmed: 31539636
N Engl J Med. 2019 Apr 4;380(14):1347-1358
pubmed: 30943338
Intensive Care Med. 2020 Aug;46(8):1552-1562
pubmed: 32572531
BMJ Health Care Inform. 2020 Apr;27(1):
pubmed: 32354696
Lancet Oncol. 2019 May;20(5):e262-e273
pubmed: 31044724
World J Crit Care Med. 2019 Nov 19;8(7):120-126
pubmed: 31853447
NPJ Digit Med. 2020 Mar 23;3:41
pubmed: 32219182
Immunol Rev. 2016 Nov;274(1):330-353
pubmed: 27782333
Crit Care Med. 2020 Feb;48(2):137-141
pubmed: 31939780
Appl Clin Inform. 2020 May;11(3):387-398
pubmed: 32462640
Int J Med Inform. 2019 Feb;122:55-62
pubmed: 30623784
Physiol Rev. 2013 Jul;93(3):1247-88
pubmed: 23899564
BMJ Open Qual. 2017 Oct 25;6(2):e000158
pubmed: 29450295
Crit Care Med. 2001 Jul;29(7):1303-10
pubmed: 11445675
JAMA. 2018 Apr 3;319(13):1317-1318
pubmed: 29532063
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
Antibiotics (Basel). 2020 Jan 31;9(2):
pubmed: 32023986
J Am Med Inform Assoc. 2019 Dec 1;26(12):1466-1477
pubmed: 31314892
Crit Care Med. 2016 Aug;44(8):1459-60
pubmed: 27428116
BMJ Open. 2015 Dec 23;5(12):e009487
pubmed: 26700284
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:8315-8
pubmed: 22256274
J Am Med Inform Assoc. 2020 Mar 1;27(3):437-443
pubmed: 31951005
Comput Biol Med. 2019 Dec;115:103488
pubmed: 31634699
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4038-4041
pubmed: 30441243
Crit Care Med. 2017 Nov;45(11):1946-1947
pubmed: 29028697
J Intensive Care. 2019 Feb 21;7:13
pubmed: 30828456
Front Pediatr. 2014 Jun 16;2:56
pubmed: 24982852
Sci Rep. 2017 Sep 7;7(1):10800
pubmed: 28883645
J Burn Care Res. 2007 Nov-Dec;28(6):776-90
pubmed: 17925660
Med Care. 2014 Jun;52(6):e39-43
pubmed: 23001437
Crit Care Med. 2019 Nov;47(11):1485-1492
pubmed: 31389839
PLoS One. 2017 Apr 6;12(4):e0174708
pubmed: 28384212
N Engl J Med. 2017 Jun 8;376(23):2235-2244
pubmed: 28528569
BMC Med Inform Decis Mak. 2020 Oct 27;20(1):276
pubmed: 33109167
Intensive Care Med. 2003 Apr;29(4):530-8
pubmed: 12664219
BMC Pediatr. 2018 Mar 15;18(1):112
pubmed: 29544449
Pulm Ther. 2020 Jun;6(1):67-77
pubmed: 32048244
Sci Rep. 2020 Jul 23;10(1):12354
pubmed: 32704168
Sci Rep. 2020 Jan 14;10(1):273
pubmed: 31937825
Crit Care Med. 2019 Nov;47(11):1477-1484
pubmed: 31135500
Sci Rep. 2019 Oct 22;9(1):15132
pubmed: 31641162
BMJ Qual Saf. 2019 Sep;28(9):693-696
pubmed: 31015377
JAMA. 2017 Oct 3;318(13):1241-1249
pubmed: 28903154
J Clin Monit Comput. 2019 Oct;33(5):887-893
pubmed: 30417258
J Healthc Eng. 2019 Nov 3;2019:5930379
pubmed: 31885832
JAMA. 2019 May 28;321(20):2003-2017
pubmed: 31104070
JAMIA Open. 2020 Apr 11;3(2):252-260
pubmed: 32734166
Sci Transl Med. 2015 Aug 5;7(299):299ra122
pubmed: 26246167
Comput Biol Med. 2017 Oct 1;89:248-255
pubmed: 28843829
JMIR Mhealth Uhealth. 2019 Aug 02;7(8):e11966
pubmed: 31376272
J Leg Med. 2019 Oct-Dec;39(4):427-441
pubmed: 31940250
JAMA. 2019 May 28;321(20):1981-1982
pubmed: 31104067
Artif Intell Med. 2020 Apr;104:101820
pubmed: 32498999
BMC Emerg Med. 2016 Aug 22;16(1):31
pubmed: 27549755
JMIR Med Inform. 2016 Sep 30;4(3):e28
pubmed: 27694098
Comput Biol Med. 2019 Jun;109:79-84
pubmed: 31035074
Clin Microbiol Infect. 2020 Oct;26(10):1291-1299
pubmed: 32061798
Crit Care Med. 2018 Apr;46(4):547-553
pubmed: 29286945
N Engl J Med. 2015 Apr 23;372(17):1629-38
pubmed: 25776936
J Am Med Inform Assoc. 2014 Mar-Apr;21(2):326-36
pubmed: 24043317
IEEE J Biomed Health Inform. 2019 May;23(3):978-986
pubmed: 30676988
Biomed Eng Online. 2018 Nov 20;17(Suppl 1):135
pubmed: 30458795
Comput Biol Med. 2016 Jul 1;74:69-73
pubmed: 27208704
Sci Data. 2016 May 24;3:160035
pubmed: 27219127
F1000Res. 2019 Oct 8;8:1728
pubmed: 31824670
Intensive Care Med. 2020 Mar;46(3):383-400
pubmed: 31965266
BMJ Open. 2018 Jan 26;8(1):e017833
pubmed: 29374661
AMIA Annu Symp Proc. 2013 Nov 16;2013:1109-15
pubmed: 24551396
Crit Care Med. 1992 Jun;20(6):864-74
pubmed: 1597042
Intensive Care Med. 1996 Jul;22(7):707-10
pubmed: 8844239
Crit Care Med. 2018 Apr;46(4):612-618
pubmed: 29369828
Crit Care Med. 2014 Mar;42(3):625-31
pubmed: 24201173
J Crit Care. 2020 Feb;55:163-170
pubmed: 31734491
J Pediatr. 2020 Feb;217:145-151.e6
pubmed: 31733815
Comput Biol Med. 2019 Oct;113:103395
pubmed: 31480008
PLoS One. 2019 Feb 22;14(2):e0212665
pubmed: 30794638
PLoS One. 2019 Feb 13;14(2):e0211057
pubmed: 30759094
Medicine (Baltimore). 2019 Apr;98(16):e15276
pubmed: 31008972
Am J Respir Crit Care Med. 2016 Feb 1;193(3):259-72
pubmed: 26414292
Biomed Inform Insights. 2019 Nov 04;11:1178222619885147
pubmed: 31700248
Rev Bras Ter Intensiva. 2017 Jan-Mar;29(1):4-8
pubmed: 28444066
Chest. 2017 Feb;151(2):278-285
pubmed: 27452768
J Hosp Med. 2010 Jan;5(1):19-25
pubmed: 20063402
J Electrocardiol. 2017 Nov - Dec;50(6):739-743
pubmed: 28916175
BMJ Open Respir Res. 2017 Nov 9;4(1):e000234
pubmed: 29435343
JAMA. 2020 Apr 21;323(15):1478-1487
pubmed: 32207816
Int J Med Inform. 2020 Sep;141:104176
pubmed: 32485555