Non-pharmaco, non-invasive management of coronary no-reflow phenomenon.
TIMI flow
TIMI frame count
acute coronary syndromes
autologous blood transfusion
no-reflow
percutaneous coronary intervention
Journal
Archives of medical sciences. Atherosclerotic diseases
ISSN: 2451-0629
Titre abrégé: Arch Med Sci Atheroscler Dis
Pays: Poland
ID NLM: 101701205
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
07
2020
accepted:
30
08
2020
entrez:
1
3
2021
pubmed:
2
3
2021
medline:
2
3
2021
Statut:
epublish
Résumé
No-reflow is an infrequent but dreaded complication of percutaneous coronary intervention (PCI), where the culprit is obstruction of the downstream microvascular bed. The aim of this study was to evaluate the efficacy and safety of forceful injection of blood (autologous blood transfusion - ABT) in reversing no-reflow during PCI because data regarding its effectiveness is not available. 100-120 ml of blood was withdrawn through guiding catheter over 3 to 5 min using a 10 ml syringe and re-infused by forceful injection over 3 min through it, and its efficacy was assessed at 10 min using TIMI flow grade and quantitative corrected TIMI frame count. In total 93 patients received ABT following no-reflow. Their clinical presentation was ST-elevation myocardial infarction (STEMI) ( In this largest and only study to date, ABT is a safe and highly effective approach to reverse no-reflow by raising driving pressure across the capillary bed.
Identifiants
pubmed: 33644485
doi: 10.5114/amsad.2020.102424
pii: 42955
pmc: PMC7885815
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e271-e278Informations de copyright
Copyright: © 2020 Termedia & Banach.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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