A randomized double-blind controlled trial of everolimus in individuals with

Autism spectrum disorder Everolimus Neurobehavior and neurocognition PTEN hamartoma tumor syndrome Randomized controlled trial

Journal

Contemporary clinical trials communications
ISSN: 2451-8654
Titre abrégé: Contemp Clin Trials Commun
Pays: Netherlands
ID NLM: 101671157

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 13 08 2020
revised: 03 01 2021
accepted: 16 01 2021
entrez: 1 3 2021
pubmed: 2 3 2021
medline: 2 3 2021
Statut: epublish

Résumé

This randomized, double-blind controlled trial of everolimus in individuals with germline phosphatase and tensin homolog mutations (

Identifiants

DOI: 10.1016/j.conctc.2021.100733 PMID: 33644493 PMC: PMC7887633
pubmed: 33644493
doi: 10.1016/j.conctc.2021.100733
pii: S2451-8654(21)00035-1
pmc: PMC7887633
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100733

Subventions

Organisme : NICHD NIH HHS
ID : P50 HD105351
Pays : United States
Organisme : NINDS NIH HHS
ID : U54 NS092090
Pays : United States

Informations de copyright

© 2021 The Author(s).

Déclaration de conflit d'intérêts

Authors declare no conflict of interest.

Références

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Auteurs

Antonio Y Hardan (AY)

Department of Psychiatry and Behavioral Science, Stanford University, Stanford, CA, USA.

Booil Jo (B)

Department of Psychiatry and Behavioral Science, Stanford University, Stanford, CA, USA.

Thomas W Frazier (TW)

Autism Speaks, New York, NY, USA.
Department of Psychology, John Carroll University, Cleveland Heights, Ohio, USA.
Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Patricia Klaas (P)

Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Robyn M Busch (RM)

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.

Kira A Dies (KA)

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Rajna Filip-Dhima (R)

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Anne V Snow (AV)

Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Charis Eng (C)

Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
Department of Pediatric Hematology Oncology and Bone Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Germline High Risk Cancer Focus Group, Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Rabi Hanna (R)

Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Bo Zhang (B)

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Mustafa Sahin (M)

Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Classifications MeSH