Highly accelerated subtractive femoral non-contrast-enhanced MRA using compressed sensing with k-space subtraction, phase and intensity correction.


Journal

Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245

Informations de publication

Date de publication:
07 2021
Historique:
revised: 25 01 2021
received: 27 09 2020
accepted: 25 01 2021
pubmed: 2 3 2021
medline: 21 5 2021
entrez: 1 3 2021
Statut: ppublish

Résumé

To develop an improved reconstruction method, k-space subtraction with phase and intensity correction (KSPIC), for highly accelerated, subtractive, non-contrast-enhanced MRA. The KSPIC method is based on k-space subtraction of complex raw data. It applies a phase-correction procedure to restore the polarity of negative signals caused by subtraction and an intensity-correction procedure to improve background suppression and thereby sparsity. Ten retrospectively undersampled data sets and 10 groups of prospectively undersampled data sets were acquired in 12 healthy volunteers. The performance of KSPIC was compared with another improved reconstruction based on combined magnitude subtraction, as well as with conventional k-space subtraction reconstruction and magnitude subtraction reconstruction, both using quantitative metrics and using subjective quality scoring. In the quantitative evaluation, KSPIC had the best performance in terms of peak SNR, structural similarity index measure, contrast-to-noise ratio of artery-to-background and sharpness, especially at high acceleration factors. The KSPIC method also had the highest subjective scores for all acceleration factors in terms of vessel delineation, image noise and artifact, and background contamination. The acquisition can be accelerated by a factor of 20 without significant decreases of subjective scores. The optimal size of the phase-correction region was found to be 12-20 pixels in this study. Compared with combined magnitude subtraction and conventional reconstructions, KSPIC has the best performance in all of the quantitative and qualitative measurements, permitting good image quality to be maintained up to higher accelerations. The KSPIC method has the potential to further reduce the acquisition time of subtractive MRA for clinical examinations.

Identifiants

pubmed: 33645815
doi: 10.1002/mrm.28736
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

320-334

Subventions

Organisme : Department of Health
ID : BRC-1215-20014
Pays : United Kingdom

Informations de copyright

© 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

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Auteurs

Hao Li (H)

Department of Radiology, University of Cambridge, Cambridge, United Kingdom.

Martin J Graves (MJ)

Department of Radiology, University of Cambridge, Cambridge, United Kingdom.
Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom.

Nadeem Shaida (N)

Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom.

Akash Prashar (A)

Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom.

David J Lomas (DJ)

Department of Radiology, University of Cambridge, Cambridge, United Kingdom.
Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom.

Andrew N Priest (AN)

Department of Radiology, University of Cambridge, Cambridge, United Kingdom.
Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom.

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