Rosacea.

Erythematotelangiectatic Ocular Papulopustular Pathophysiology Phymatous Rhinophyma Rosacea

Journal

British journal of hospital medicine (London, England : 2005)
ISSN: 1750-8460
Titre abrégé: Br J Hosp Med (Lond)
Pays: England
ID NLM: 101257109

Informations de publication

Date de publication:
02 Feb 2021
Historique:
entrez: 1 3 2021
pubmed: 2 3 2021
medline: 30 9 2021
Statut: ppublish

Résumé

Rosacea is a common cutaneous condition affecting predominantly the face. It is historically characterised into four subtypes: erythematotelangiectatic, papulopustular, phymatous and ocular rosacea. This article describes the pathophysiology, clinical features and current treatment options for rosacea, and discusses updated diagnostic criteria. General guidance is required on the need to avoid possible triggers including dietary and environmental triggers. The strongest evidence supports the use of 0.75% metronidazole, topical azelaic acid or topical ivermectin for inflammatory rosacea. Erythema should be treated with brimonidine tartrate gel, oral medication such as beta blockers or vascular laser and light-based therapy. Oral doxycycline 40 mg modified release can be used as monotherapy or in combination with other treatments for recalcitrant disease. Further understanding of the pathogenesis of rosacea could allow identification and targeted avoidance of triggers and the development of new treatment modalities.

Identifiants

pubmed: 33646026
doi: 10.12968/hmed.2020.0417
doi:

Substances chimiques

Dermatologic Agents 0
Metronidazole 140QMO216E
Doxycycline N12000U13O

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-8

Auteurs

Tamara Searle (T)

University of Birmingham Medical School, Birmingham, UK.

Firas Al-Niaimi (F)

Department of Dermatology, Aalborg University Hospital, Aalborg, Denmark.

Faisal R Ali (FR)

Dermatological Surgery & Laser Unit, St John's Institute of Dermatology, Guy's Hospital Cancer Centre, Guy's and St Thomas' NHS Foundation Trust, London.

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Classifications MeSH