Association between dental extraction after radiotherapy and osteoradionecrosis: A multi-centre retrospective study.


Journal

Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565

Informations de publication

Date de publication:
May 2022
Historique:
revised: 12 02 2021
received: 30 09 2020
accepted: 16 02 2021
pubmed: 3 3 2021
medline: 29 4 2022
entrez: 2 3 2021
Statut: ppublish

Résumé

Radiotherapy (RT) carries a substantial risk for the development of osteoradionecrosis (ORN) of the jaw. This study was performed to investigate the relationship between dental extractions after RT and the development of ORN. Thirty-two patients with head and neck cancer who underwent tooth extraction after RT were investigated for correlations between the development of ORN and various factors. Postextraction ORN was diagnosed in 12 (12.1%) teeth of 9 patients. The RT dose against the site of tooth extraction was 62.0 and 37.4 Gy in the ORN and Non-ORN groups, respectively (p < .001). The duration from RT to tooth extraction was 41.2 and 28.2 months in the ORN and Non-ORN groups, respectively (p = .025). Tooth extraction was significantly associated with ORN in patients with a high RT dose against the site (odds ratio = 1.231) and a longer duration of time from RT (odds ratio = 1.084). Extraction of non-restorable teeth and those with a poor prognosis should not necessarily be postponed even when patients are undergoing RT. However, clinicians should pay special attention to postoperative management after tooth extraction in patients with a high RT dose and longer time from RT.

Identifiants

pubmed: 33650256
doi: 10.1111/odi.13826
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Pagination

1181-1187

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

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Auteurs

Izumi Saito (I)

Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Takumi Hasegawa (T)

Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Yumiko Kawashita (Y)

Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.

Shinichiro Kato (S)

Department of Oral and Maxillofacial Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Shin-Ichi Yamada (SI)

Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Yuka Kojima (Y)

Department of Dentistry and Oral Surgery, Kansai Medical University, Hirakata, Japan.

Nobuhiro Ueda (N)

Department of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Japan.

Masahiro Umeda (M)

Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan.

Yasuyuki Shibuya (Y)

Department of Oral and Maxillofacial Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Hiroshi Kurita (H)

Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Tadaaki Kirita (T)

Department of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, Japan.

Masaya Akashi (M)

Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

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