Gamma camera characterization at high holmium-166 activity in liver radioembolization.
166Holmium
Dosimetry
High-count rate
Radioembolization
Scatter correction
Journal
EJNMMI physics
ISSN: 2197-7364
Titre abrégé: EJNMMI Phys
Pays: Germany
ID NLM: 101658952
Informations de publication
Date de publication:
02 Mar 2021
02 Mar 2021
Historique:
received:
12
08
2020
accepted:
23
02
2021
entrez:
2
3
2021
pubmed:
3
3
2021
medline:
3
3
2021
Statut:
epublish
Résumé
High activities of holmium-166 ( A 20% count loss due to dead time was observed around 0.7 GBq in the photopeak window. Independent of the count losses, the measured activity concentration was up to 100% of the real value for non-tumorous liver, when reconstructions were normalized to the known activity at scanning time. However, for tumor spheres, activity concentration recovery was ~80% at the lowest activity, decreasing with increasing activity in the phantom. Measured lung shunt fractions were relatively constant over the considered activity range. At high
Sections du résumé
BACKGROUND
BACKGROUND
High activities of holmium-166 (
RESULTS
RESULTS
A 20% count loss due to dead time was observed around 0.7 GBq in the photopeak window. Independent of the count losses, the measured activity concentration was up to 100% of the real value for non-tumorous liver, when reconstructions were normalized to the known activity at scanning time. However, for tumor spheres, activity concentration recovery was ~80% at the lowest activity, decreasing with increasing activity in the phantom. Measured lung shunt fractions were relatively constant over the considered activity range.
CONCLUSIONS
CONCLUSIONS
At high
Identifiants
pubmed: 33651253
doi: 10.1186/s40658-021-00372-9
pii: 10.1186/s40658-021-00372-9
pmc: PMC7925770
doi:
Types de publication
Journal Article
Langues
eng
Pagination
22Subventions
Organisme : Nederlandse Organisatie voor Wetenschappelijk Onderzoek
ID : Project Number NWA.ID.17.059
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