Effect of L-glutamic acid N,N-diacetic acid on the availability of dietary zinc in broiler chickens.
GLDA
bioavailability
broiler
chelator
zinc
Journal
Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
10
06
2020
revised:
03
12
2020
accepted:
04
12
2020
entrez:
3
3
2021
pubmed:
4
3
2021
medline:
15
5
2021
Statut:
ppublish
Résumé
Chelating agents can be used to improve the nutritional availability of trace minerals within the gastrointestinal tract. This study was conducted to determine the effect of a novel chelating agents, L-glutamic acid N,N-diacetic acid (GLDA), a biodegradable alternative to ethylenediaminetetraacetic acid on the nutritional bioavailability of zinc in broilers. Twelve dietary treatments were allocated to 96 pens in a randomized block design. Pens contained 10 Ross 308 male broilers in a factorial design with 6 incremental zinc levels (40, 45, 50, 60, 80, and 120 ppm of total Zn), with and without inclusion of GLDA (0 and 100 ppm) as respective factors. Experimental diets were supplied from day 7 to 21/22 and serum, liver and tibia Zn content were determined in 3 birds per pen. Growth performance and liver characteristics were not affected by dietary treatments, but both supplemental Zn and GLDA enhanced tibia and serum zinc concentration. The positive effect of GLDA was observed at all levels of the dietary Zn addition. The amount of zinc needed to reach 95% of the asymptotic Zn response was determined using nonlinear regression. When GLDA was included in the diet, based on tibia Zn, the same Zn status was achieved with a 19 ppm smaller Zn dose while based on serum Zn this was 27 ppm less Zn. Dietary GLDA reduces supplemental Zn needs to fulfill nutritional demands as defined by tibia Zn and serum Zn response. Considering the positive effect on the nutritional availability of Zn in broilers, GLDA presents an opportunity as biodegradable additive, to reduce Zn supplementation to livestock and thereby reducing Zn excretion into the environment, while fulfilling the nutrition Zn needs of farmed animals.
Identifiants
pubmed: 33652535
pii: S0032-5791(20)30964-0
doi: 10.1016/j.psj.2020.12.013
pmc: PMC7936176
pii:
doi:
Substances chimiques
Glutamic Acid
3KX376GY7L
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100913Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
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