Electron-Induced Decomposition of Uracil-5-yl

electron attachment gas phase low-energy electrons radiosensitizers resonance energy uracil derivatives

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 Feb 2021
Historique:
received: 02 02 2021
revised: 18 02 2021
accepted: 21 02 2021
entrez: 3 3 2021
pubmed: 4 3 2021
medline: 20 4 2021
Statut: epublish

Résumé

The incorporation of modified uracil derivatives into DNA leads to the formation of radical species that induce DNA damage. Molecules of this class have been suggested as radiosensitizers and are still under investigation. In this study, we present the results of dissociative electron attachment to uracil-5-yl

Identifiants

pubmed: 33652878
pii: ijms22052344
doi: 10.3390/ijms22052344
pmc: PMC7956691
pii:
doi:

Substances chimiques

Gases 0
Radiation-Sensitizing Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Austrian Science Fund FWF
ID : P 30332
Pays : Austria
Organisme : Austrian Science Fund
ID : P30332
Organisme : Polish National Science Center (NCN)
ID : UMO-2014/14/A/ST4/00405

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Auteurs

Eugene Arthur-Baidoo (E)

Institute for Ion Physics and Applied Physics, University of Innsbruck, Technikerstrasse 25/3, 6020 Innsbruck, Austria.
Center for Biomolecular Sciences Innsbruck, University of Innsbruck, Technikerstrasse 25/3, 6020 Innsbruck, Austria.

Karina Falkiewicz (K)

Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.

Lidia Chomicz-Mańka (L)

Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.

Anna Czaja (A)

Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.

Sebastian Demkowicz (S)

Department of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.

Karol Biernacki (K)

Department of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland.

Witold Kozak (W)

Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.

Janusz Rak (J)

Department of Physical Chemistry, Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308 Gdańsk, Poland.

Stephan Denifl (S)

Institute for Ion Physics and Applied Physics, University of Innsbruck, Technikerstrasse 25/3, 6020 Innsbruck, Austria.
Center for Biomolecular Sciences Innsbruck, University of Innsbruck, Technikerstrasse 25/3, 6020 Innsbruck, Austria.

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