Propensity-Adjusted Comparison of Mortality of Elderly Versus Very Elderly Ventilated Patients.
ICU
critically ill
elderly subjects
mechanical ventilation
risk scores
risk stratification
Journal
Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
pubmed:
4
3
2021
medline:
20
5
2021
entrez:
3
3
2021
Statut:
ppublish
Résumé
The growing proportion of elderly intensive care patients constitutes a public health challenge. The benefit of critical care in these patients remains unclear. We compared outcomes in elderly versus very elderly subjects receiving mechanical ventilation. In total, 5,557 mechanically ventilated subjects were included in our post hoc retrospective analysis, a subgroup of the VENTILA study. We divided the cohort into 2 subgroups on the basis of age: very elderly subjects (age ≥ 80 y; Very elderly subjects were clinically sicker as expressed by higher SAPS II scores (53 ± 18 vs 50 ± 18, Age was an independent and unchangeable risk factor for death in mechanically ventilated subjects. However, survival rates of very elderly subjects were > 50%. Denial of critical care based solely on age is not justified. (ClinicalTrials.gov registration NCT02731898.).
Sections du résumé
BACKGROUND
BACKGROUND
The growing proportion of elderly intensive care patients constitutes a public health challenge. The benefit of critical care in these patients remains unclear. We compared outcomes in elderly versus very elderly subjects receiving mechanical ventilation.
METHODS
METHODS
In total, 5,557 mechanically ventilated subjects were included in our post hoc retrospective analysis, a subgroup of the VENTILA study. We divided the cohort into 2 subgroups on the basis of age: very elderly subjects (age ≥ 80 y;
RESULTS
RESULTS
Very elderly subjects were clinically sicker as expressed by higher SAPS II scores (53 ± 18 vs 50 ± 18,
CONCLUSIONS
CONCLUSIONS
Age was an independent and unchangeable risk factor for death in mechanically ventilated subjects. However, survival rates of very elderly subjects were > 50%. Denial of critical care based solely on age is not justified. (ClinicalTrials.gov registration NCT02731898.).
Identifiants
pubmed: 33653910
pii: respcare.08547
doi: 10.4187/respcare.08547
doi:
Banques de données
ClinicalTrials.gov
['NCT02731898']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
814-821Informations de copyright
Copyright © 2021 by Daedalus Enterprises.
Déclaration de conflit d'intérêts
The authors have disclosed no conflicts of interest.