Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
02 03 2021
Historique:
received: 16 11 2020
accepted: 15 02 2021
entrez: 3 3 2021
pubmed: 4 3 2021
medline: 15 12 2021
Statut: epublish

Résumé

To clip or coil has been matter of debates for several years and is the domain of interdisciplinary decision making. However, the microsurgical outcome has still been elusive concerning wide neck aneurysms (WNA). A retrospective single center study was performed with all patients with ruptured WNA (rWNA) and unruptured WNA (uWNA) admitted to author´s institute between 2007-2017. Microsurgical outcome was evaluated according to Raymond-Roy occlusion grade and follow-up angiography was performed to analyze the stability of neck/aneurysm remnants and retreatment poverty. Of 805 aneurysms, 139 were rWNA (17.3%) and 148 uWNA (18.4%). Complete occlusion was achieved in 102 of 139 rWNA (73.4%) and 112 of 148 uWNA (75.6%). Neck remnants were observed in 36 patients with rWNA (25.9%) and 30 patients with uWNA (20.3%), 1 (0.7%) and 6 (4.1%) patients had aneurysmal remnant, respectively. Overall complication rate was 11.5%. At follow-up (939/1504 months), all remnants were stable except for one, which was further conservatively treated with marginal retreatment rate under 1%. Even the risk of de-novo aneurysm was higher than the risk for remnant growth (2.6% vs 0% in rWNA; 8.7% vs 5.3% in uWNA) without significant difference. Microsurgical clipping is effective for complete occlusion of r/uWNA with low complication. Furthermore, the risk of remnant growth is marginal even lower than the risk of de-novo rate low retreatment rate.

Identifiants

pubmed: 33654126
doi: 10.1038/s41598-021-84339-x
pii: 10.1038/s41598-021-84339-x
pmc: PMC7925666
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4982

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Auteurs

Sae-Yeon Won (SY)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany. sae-yeon.won@kgu.de.

Volker Seifert (V)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

Daniel Dubinski (D)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

Sepide Kashefiolasl (S)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

Nazife Dinc (N)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

Markus Bruder (M)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

Juergen Konczalla (J)

Department of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.

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Classifications MeSH