Edema-mass Ratio Based On Magnetic Resonance Imaging As A Preoperative Diagnostic Factor For Posterior Fossa Metastasis.
Edema
magnetic resonance imaging
metastasis
posterior fossa
prognostic factor
survival.
Journal
Current medical imaging
ISSN: 1573-4056
Titre abrégé: Curr Med Imaging
Pays: United Arab Emirates
ID NLM: 101762461
Informations de publication
Date de publication:
2021
2021
Historique:
received:
28
12
2020
revised:
21
01
2021
accepted:
17
02
2021
pubmed:
4
3
2021
medline:
27
10
2021
entrez:
3
3
2021
Statut:
ppublish
Résumé
Peritumoral edema of primary brain tumors is an important cause of morbidity and mortality. The number of studies currently available on the prognostic role of peritumoral brain edema in the posterior fossa is extremely limited. Based on the known importance of magnetic resonance imaging in diagnosing supratentorial metastases, this study aimed to investigate the effects of peritumoral edema on survival of patients with posterior fossa metastases and the preoperative diagnostic value of MRI. Edema and mass volumes of 49 patients with posterior fossa metastasis, who underwent surgery during 2012-2016, were measured using magnetic resonance imaging. The edema/mass indices were retrospectively calculated and interpreted by evaluating the demographic, clinical, and survival data. The study consisted of 32 (65.3%) male and 17 (34.7%) female participants, with the mean age ± standard deviation of 47.25±29.25 (17-81) years. Among the 49 patients with posterior fossa metastases, 34 (69.4%) had carcinoma, while 15 (30.6%) had non-carcinoma metastases. The edema/mass indices of patients with carcinoma and non-carcinoma metastases were found to be 14.55±9.64 and 1.34±1.08, respectively, and the difference was statistically significant (p<0.001). The mean survival of patients with carcinoma and non-carcinoma metastases was found to be 642±11.52 days and 726±9.32 days, respectively; however, this difference was not statistically significant (p=0.787). The edema/mass ratio was found to be a significant diagnostic factor for the prediction of posterior fossa metastases. Further detailed studies are warranted to investigate the effect of edema/mass ratio on survival rate.
Sections du résumé
BACKGROUND
Peritumoral edema of primary brain tumors is an important cause of morbidity and mortality. The number of studies currently available on the prognostic role of peritumoral brain edema in the posterior fossa is extremely limited.
OBJECTIVE
Based on the known importance of magnetic resonance imaging in diagnosing supratentorial metastases, this study aimed to investigate the effects of peritumoral edema on survival of patients with posterior fossa metastases and the preoperative diagnostic value of MRI.
METHODS
Edema and mass volumes of 49 patients with posterior fossa metastasis, who underwent surgery during 2012-2016, were measured using magnetic resonance imaging. The edema/mass indices were retrospectively calculated and interpreted by evaluating the demographic, clinical, and survival data.
RESULTS
The study consisted of 32 (65.3%) male and 17 (34.7%) female participants, with the mean age ± standard deviation of 47.25±29.25 (17-81) years. Among the 49 patients with posterior fossa metastases, 34 (69.4%) had carcinoma, while 15 (30.6%) had non-carcinoma metastases. The edema/mass indices of patients with carcinoma and non-carcinoma metastases were found to be 14.55±9.64 and 1.34±1.08, respectively, and the difference was statistically significant (p<0.001). The mean survival of patients with carcinoma and non-carcinoma metastases was found to be 642±11.52 days and 726±9.32 days, respectively; however, this difference was not statistically significant (p=0.787).
CONCLUSION
The edema/mass ratio was found to be a significant diagnostic factor for the prediction of posterior fossa metastases. Further detailed studies are warranted to investigate the effect of edema/mass ratio on survival rate.
Identifiants
pubmed: 33655873
pii: CMIR-EPUB-114695
doi: 10.2174/1573405617666210303105006
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
762-766Informations de copyright
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