[PECULIARITIES OF CEREBRAL HEMODYNAMICS IN PATIENTS WITH CHRONIC CEREBRAL VENOUS DYSFUNCTION SYNDROME AND DIFFERENT ARTERIAL PRESSURE LEVELS].

For the purpose of research and comparative analysis of the features of cerebral blood flow, determined by the ultrasonic duplex scanning (USDS) method, in persons with clinical signs of chronic cerebral venous dysfunction syndrome and different levels of arterial pressure (AP), ultrasound of the head and neck was performed in 104 patients. 78 people - the main group (MG), where patients were selected for clinical signs of the presence of chronic cerebral venous dysfunction syndrome (CCVDS) and different blood pressure levels, were divided into 3 clinical groups: 33 people - people with high blood pressure (157.2±12,2/98.3±4.2) - hypertensive patients; 24 people with labile blood pressure with predominantly normal average blood pressure (125.23±12.2/82.22±4.14) - conditional normotonics; 21 people with low blood pressure (100.32±7.23/65.45±6.4) were hypotonic. Also, 26 patients of the comparison group were recruited - people without clinical signs of CCVDS and different levels of blood pressure, distributed according to the same principle: hypertensive patients - 8 people, normotonic patients - 13 people, hypotensive patients - 5 people. The total age of the patients ranged from 35 to 65 years (mean age 53.60±10.27 years). Among the patients there were 82 women and 22 men. Statistical comparison was performed using Fisher's exact test. The mean velocity indices of cerebral blood flow with varying degrees of reliability, depending on the level of arterial pressure, differed in patients with chronic cerebral venous dysfunction syndrome versus the indices of the comparison groups. The presence of clinical signs of CCVDS in people with different blood pressure levels was accompanied by a significant slowdown in blood flow in most cerebral arteries and a significant acceleration in the Rosenthal vein compared with patients without clinical manifestations of venous dysfunction and with the same arterial pressure. Attention was drawn to the fact that in persons with increased blood pressure, in contrast to the rest of the patients, a statistically significant acceleration of the linear blood flow velocity in vertebral artery at the level of the second cervical vertebra (VA2) was observed (p<0.05). In the subgroups of hypertensive patients with CCVDS, the mean linear blood flow velocity with a significant difference was twice less than the comparison group: a significant decrease in velocity parameters was only in the middle cerebral arteriasis (MCA) basins on both sides (p<0.01, p<0.05 on the right and left, respectively) and on the left in the pools posterior cerebral artery (PCA), VA2, a significant increase in blood flow (p<0.01, p<0.05) - in the veins of Rosenthal (VR). This discrepancy can be explained by the fact that hypertensive patients from the comparison group, that is, without clinical symptoms of CCVDS, already have subclinical manifestations of CCVDS, as evidenced by changes in the USDS indicators.