Preparation of Bacterial Outer Membrane Vesicles for Characterisation of Periplasmic Proteins in Their Native Environment.

Gram-negative bacteria In-situ protein studies NMR spectroscopy Outer membrane vesicles Periplasm

Journal

Bio-protocol
ISSN: 2331-8325
Titre abrégé: Bio Protoc
Pays: United States
ID NLM: 101635102

Informations de publication

Date de publication:
20 Dec 2020
Historique:
received: 30 06 2020
revised: 26 10 2020
accepted: 28 10 2020
entrez: 4 3 2021
pubmed: 5 3 2021
medline: 5 3 2021
Statut: epublish

Résumé

Bacterial outer membrane vesicles (OMVs) are naturally formed by budding from the outer membrane of Gram-negative bacteria. OMVs consist of a lipid bilayer identical in composition to the original outer membrane and contain periplasmic content within their lumen. Enriched with specific envelope proteins, OMVs make for an excellent native-like platform to study these proteins

Identifiants

pubmed: 33659500
doi: 10.21769/BioProtoc.3853
pii: e3853
pmc: PMC7842343
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e3853

Informations de copyright

Copyright © 2020 The Authors; exclusive licensee Bio-protocol LLC.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing interest.

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Auteurs

Johannes Thoma (J)

Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, 405 30 Göteborg, Sweden.
Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden.

Björn M Burmann (BM)

Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, 405 30 Göteborg, Sweden.
Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden.

Classifications MeSH