Recent advances in understanding cholangiocarcinoma.
Cholangiocarcinoma
FGFR2
IDH1
PD-1
biliary tract cancer
Journal
Faculty reviews
ISSN: 2732-432X
Titre abrégé: Fac Rev
Pays: England
ID NLM: 101769226
Informations de publication
Date de publication:
2020
2020
Historique:
entrez:
4
3
2021
pubmed:
5
3
2021
medline:
5
3
2021
Statut:
epublish
Résumé
The definition of cholangiocarcinoma (CCA) encompasses all tumors originating in the epithelium of the bile ducts, including the intrahepatic bile ducts (ICCA) and extrahepatic bile ducts (ECCA). The incidence of ICCA and ECCA has increased in the last few decades, and molecular advances in both entities have brought understanding of their differences and allowed treatment advances aimed at personalized therapy. In this review, we discuss recent progress in the molecular landscape of CCAs, emerging treatment biomarker-guided strategies, and future insights into the management of advanced disease.
Identifiants
pubmed: 33659947
doi: 10.12703/b/9-15
pmc: PMC7886064
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
15Informations de copyright
Copyright: © 2020 Borad MJ et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.
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