Delivery by caesarean section and offspring adiposity and cardio-metabolic health at ages 6.5, 11.5 and 16 years: results from the PROBIT cohort in Belarus.
body mass index
caesarean section
child
mode of delivery
obesity
Journal
Pediatric obesity
ISSN: 2047-6310
Titre abrégé: Pediatr Obes
Pays: England
ID NLM: 101572033
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
01
02
2021
received:
01
10
2020
accepted:
08
02
2021
pubmed:
5
3
2021
medline:
15
12
2021
entrez:
4
3
2021
Statut:
ppublish
Résumé
Caesarean delivery has been associated with later adiposity, perhaps via early programming or perhaps because of residual confounding by maternal or birth characteristics. Examine associations of caesarean delivery with adiposity and cardio-metabolic biomarkers. Observational analysis of 15 069 children in the PROBIT cohort in Belarus. We examined measures of child anthropometry and blood pressure at 6.5, 11.5 and 16 years and fasting blood (11.5 years). Caesarean-delivered children were slightly heavier at 6.5 (mean BMI 15.8 vs. 15.6 kg/m Caesarean delivery had little or no association with adiposity or related cardio-metabolic biomarkers in childhood. Adjustment for maternal BMI attenuated all outcome effect estimates.
Sections du résumé
BACKGROUND
Caesarean delivery has been associated with later adiposity, perhaps via early programming or perhaps because of residual confounding by maternal or birth characteristics.
OBJECTIVES
Examine associations of caesarean delivery with adiposity and cardio-metabolic biomarkers.
METHODS
Observational analysis of 15 069 children in the PROBIT cohort in Belarus. We examined measures of child anthropometry and blood pressure at 6.5, 11.5 and 16 years and fasting blood (11.5 years).
RESULTS
Caesarean-delivered children were slightly heavier at 6.5 (mean BMI 15.8 vs. 15.6 kg/m
CONCLUSIONS
Caesarean delivery had little or no association with adiposity or related cardio-metabolic biomarkers in childhood. Adjustment for maternal BMI attenuated all outcome effect estimates.
Types de publication
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12783Subventions
Organisme : CIHR
ID : MOP-53155
Pays : Canada
Organisme : NICHD NIH HHS
ID : K24 HD069408
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK092924
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD050758
Pays : United States
Informations de copyright
© 2021 World Obesity Federation.
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