68Ga-DOTATOC PET/CT in Pleural Solitary Fibrous Tumors.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 06 2021
01 06 2021
Historique:
pubmed:
5
3
2021
medline:
21
5
2021
entrez:
4
3
2021
Statut:
ppublish
Résumé
Solitary fibrous tumor of the pleura (SFTP) is a rare mesenchymal neoplasm. Preoperative diagnosis is usually difficult and based on radiological findings only. We report the imaging results observed in 5 patients with SFTP (2 malignant) obtained by 68Ga-DOTATOC PET/CT. At qualitative analysis, all tumors showed uptake of 68Ga-DOTATOC. Mean tumor SUVmax was 9.9 ± 5.7. The expression of SST2 (somatostatin receptors subtype 2) was confirmed by immunohistochemistry in 2 tumor samples, and by gene amplification of SST2 mRNA in all cases. These data suggest a diagnostic role of radioreceptor PET/CT in SFTP, and open novel potential treatment options in unresectable/metastatic disease.
Identifiants
pubmed: 33661200
doi: 10.1097/RLU.0000000000003570
pii: 00003072-202106000-00034
doi:
Substances chimiques
Organometallic Compounds
0
Receptors, Somatostatin
0
gallium Ga 68 dotatate
9L17Y0H71P
somatostatin receptor 2
D73QL0OMU2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e336-e338Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
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