Current indications for adjuvant treatment following transoral laser microsurgery of early and intermediate laryngeal cancer.
Journal
Current opinion in otolaryngology & head and neck surgery
ISSN: 1531-6998
Titre abrégé: Curr Opin Otolaryngol Head Neck Surg
Pays: United States
ID NLM: 9417024
Informations de publication
Date de publication:
01 04 2021
01 04 2021
Historique:
entrez:
5
3
2021
pubmed:
6
3
2021
medline:
26
10
2021
Statut:
ppublish
Résumé
This review summarizes the information in the literature on the indications for adjuvant therapy after transoral laser microsurgery (TLM) for early/intermediate stage laryngeal cancer. A high rate of 'nonevaluable' margins after TLM significantly complicates decision-making concerning adjuvant therapy. However, consensus grows that second-look TLM in patients with multiple superficial and deep positive margins is more sensible than sending these patients systematically for adjuvant radiotherapy (RT). The classical adagium: 'Failure to achieve negative margins indicates need for adjuvant RT' does not translate automatically to patients with glottic cancer treated by TLM. Rather, specifically patients with multiple superficial positive margins and positive deep margins after TLM need careful judging what constitutes the best additional adjuvant treatment. Second-look resection is nowadays regarded as the preferred adjuvant treatment for many of these patients whereas RT is reserved for those in whom a second look TLM is judged unlikely to result in 'true negative margins.' Additionally, when the pathology of the re-resection reveals multiple foci of residual disease or suggests again a resection with positive margins, adjuvant postoperative RT is likely to result in a better local control. If this strict selection of patients for adjuvant RT is adhered to carefully, oncological and functional results will be optimal.
Identifiants
pubmed: 33664193
doi: 10.1097/MOO.0000000000000702
pii: 00020840-202104000-00003
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
79-85Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Références
Van Eycken L. Van Eycken L. Head and neck. Cancer Burden in Belgium 2015 edn.Brussels: Belgian Cancer Registry; 2015. 32.
O'Sullivan B. Brierley J, Gospodarowicz M, Wittekind C. Head and neck tumours. The TNM classification of malignant tumours 8th edn.Oxford: Wiley Blackwell; 2017. 17–54.
Shah JP, Patel SG, Singh B, Wong RJ. Shah JP, Patel SG, Singh B, Wong RJ. Larynx and trachea. Jatin Shah's Head and Neck Surgery and Oncology 5th edn.New York: Elsevier; 2020. 365.e1.
Ferreira N, Netto E, Fonseca L, et al. Surgery versus radiotherapy: Long term outcomes of T1 glottic cancer. Rep Pract Oncol Radiother 2020; 25:860–866.
Bozec A, Culié D, Poissonnet G, Dassonville O. Current role of primary surgical treatment in patients with head and neck squamous cell carcinoma. Curr Opin Oncol 2019; 31:138–145.
Forastiere AA, Ismaila N, Lewin JS, et al. Use of larynx-preservation strategies in the treatment of laryngeal cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol 2018; 36:1143–1169.
Baird BJ, Sung CK, Beadle BM, Divi V. Treatment of early-stage laryngeal cancer: a comparison of treatment options. Oral Oncol 2018; 87:8–16.
Jäckel MC, Ambrosch P, Martin A, Steiner W. Impact of re-resection for inadequate margins on the prognosis of upper aerodigestive tract cancer treated by laser microsurgery. Laryngoscope 2007; 117:350–356.
Succo G, Crosetti E. Limitations and opportunities in open laryngeal organ preservation surgery: current role of OPHLs. Front Oncol 2019; 9:408.
Hartl DM, Ferlito A, Brasnu DF, et al. Evidence-based review of treatment options for patients with glottic cancer. Head Neck 2011; 33:1638–1648.
Peretti G, Piazza C, Mora F, et al. Reasonable limits for transoral laser microsurgery in laryngeal cancer. Curr Opin Otolaryngol Head Neck Surg 2016; 24:135–139.
Ansarin M, Cattaneo A, De Benedetto L, et al. Retrospective analysis of factors influencing oncologic outcome in 590 patients with early-intermediate glottic cancer treated by transoral laser microsurgery. Head Neck 2017; 39:71–81.
Howard J, Dwivedi RC, Masterson L, et al. De-intensified adjuvant (chemo)radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV-positive oropharyngeal carcinoma. Cochrane Database Syst Rev 2018; 12:CD012939.
Howard FM, Kochanny S, Koshy M, et al. Machine learning-guided adjuvant treatment of head and neck cancer. JAMA Netw Open 2020; 3:e2025881.
Jumaily M, Faraji F, Osazuwa-Peters N, et al. Prognostic significance of surgical margins after transoral laser microsurgery for early-stage glottic squamous cell carcinoma. Oral Oncol 2019; 97:105–111.
Peretti G, Piazza C, Penco S, et al. Transoral laser microsurgery as primary treatment for selected T3 glottic and supraglottic cancers. Head Neck 2016; 38:1107–1112.
Sjögren E. Transoral laser microsurgery in early glottic lesions. Curr Otorhinolaryngol Rep 2017; 5:56–68.
Fiz I, Mazzola F, Fiz F, et al. Impact of close and positive margins in transoral laser microsurgery for TIS-T2 glottic cancer. Front Oncol 2017; 7:16.
Meulemans J, Bijnens J, Delaere P, Vander Poorten V. Up-front and salvage transoral laser microsurgery for early glottic squamous cell carcinoma: a single centre retrospective case series. Front Oncol 2018; 8:186.
Canis M, Martin A, Ihler F, et al. Transoral laser microsurgery in treatment of pT2 and pT3 glottic laryngeal squamous cell carcinoma – results of 391 patients. Head Neck 2014; 36:859–866.
Preuss SF, Cramer K, Drebber U, et al. Second-look microlaryngoscopy to detect residual carcinoma in patients after laser surgery for T1 and T2 laryngeal cancer. Acta Otolaryngol 2009; 129:881–885.
Meulemans J, Hauben E, Peeperkorn S, et al. Transoral laser microsurgery (TLM) for glottic cancer: prospective assessment of a new pathology workup protocol. Front Surg 2020; 7:1–9.
Jäckel MC, Martin A, Steiner W. Twenty-five years experience with laser surgery for head and neck tumors: report of an international symposium, Göttingen, Germany, 2005. Eur Arch Oto-Rhino-Laryngol 2007; 264:577–585.
Gallet P, Rumeau C, Nguyen DT, et al. Watchful observation’ follow-up scheme after endoscopic CO 2 laser treatment for small glottic carcinomas: a retrospective study of 93 cases. Clin Otolaryngol 2017; 42:1193–1199.
Galli A, Giordano L, Sarandria D, et al. Analisi oncologica e delle complicanze nel trattamento endoscopico mediante laser CO2 dei tumori glottici in classe T1-T2: La nostra esperienza. Acta Otorhinolaryngol Ital 2016; 36:167–173.
Grant DG, Salassa JR, Hinni ML, et al. Transoral laser microsurgery for untreated glottic carcinoma. Otolaryngol - Head Neck Surg 2007; 137:482–486.
Hanna J, Brauer PR, Morse E, Mehra S. Margins in laryngeal squamous cell carcinoma treated with transoral laser microsurgery: a national database study. Otolaryngol Neck Surg 2019; 161:986–992.
Hendriksma M, Montagne MW, Langeveld TPM, et al. Evaluation of surgical margin status in patients with early glottic cancer (Tis-T2) treated with transoral CO2 laser microsurgery, on local control. Eur Arch Oto-Rhino-Laryngol 2018; 275:2333–2340.
Gillison ML, Haddad RI, Hicks W. Gillison ML, Haddad RI, Hicks W, et al. Head and neck cancers: cancer of the glottic larynx. NCCN Guidelines Version 1 2021 edn.2021. 44–51.
Canis M, Ihler F, Martin A, et al. Transoral laser microsurgery for T1a glottic cancer: review of 404 cases. Head Neck 2015; 37:889–895.
Peretti G, Bolzoni A, Parrinello G, et al. Analysis of recurrences in 322 TIS, T1, or T2 glottic carcinomas treated by carbon dioxide laser. Ann Otol Rhinol Laryngol 2004; 113:853–858.
Sigston E, de Mones E, Babin E, et al. Early-stage glottic cancer. Arch Otolaryngol Neck Surg 2006; 132:147–152.
Djukic V, Milovanović J, Jotić AD, et al. Laser transoral microsurgery in treatment of early laryngeal carcinoma. Eur Arch Oto-Rhino-Laryngol 2019; 276:1747–1755.
Mendenhall WM, Strojan P, Lee AW, et al. Radiotherapy in the management of glottic squamous cell carcinoma. Head Neck 2020; 42:3558–3567.
Shelan M, Anschuetz L, Schubert AD, et al. Behandlung früher Glottiskarzinome (T1–2) mit Strahlentherapie und/oder Operation. Strahlentherapie Onkol 2017; 193:995–1004.
Rödel RMW, Steiner W, Müller RM, et al. Endoscopic laser surgery of early glottic cancer: involvement of the anterior commissure. Head Neck 2009; 31:583–592.
Vaish R, Shah S, Chaukar D. Prognostic significance of surgical margins after transoral laser microsurgery for early-stage glottic cancer. Oral Oncol 2020; 100:104511.
Jacobi C, Freundorfer R, Reiter M. Transoral laser microsurgery in early glottic cancer involving the anterior commissure. Eur Arch Oto-Rhino-Laryngol 2019; 276:837–845.
Wilkie MD, Lightbody KA, Lythgoe D, et al. Transoral laser microsurgery for early and moderately advanced laryngeal cancers: outcomes from a single centralised United Kingdom centre. Eur Arch Oto-Rhino-Laryngol 2015; 272:695–704.
Forner D, Rigby MH, Corsten M, et al. Oncological and functional outcomes after repeat transoral laser microsurgery for the treatment of recurrent early glottic cancer. J Laryngol Otol 2020; 134:169–173.
Remacle M, Matar N, Delos M, et al. Is frozen section reliable in transoral CO2 laser-assisted cordectomies? Eur Arch Oto-Rhino-Laryngol 2010; 267:397–400.
Robertson S, Cooper L, McPhaden A, MacKenzie K. Refining the ‘cucumber’ technique for laryngeal biopsy. J Laryngol Otol 2011; 125:626–629.
Piazza C, Paderno A, Grazioli P, et al. Laryngeal exposure and margin status in glottic cancer treated by transoral laser microsurgery. Laryngoscope 2018; 128:1146–1151.
Ansarin M, Santoro L, Cattaneo A, et al. Laser surgery for early glottic cancer. Arch Otolaryngol Neck Surg 2009; 135:385–390.
Grant DG, Bradley PT, Parmar A, et al. Implications of positive margins or incomplete excision in laryngeal cancer treated by transoral laser microsurgery: how we do it. Clin Otolaryngol 2009; 34:485–489.
Marchi F, Filauro M, Missale F, et al. A Multidisciplinary team guided approach to the management of cT3 laryngeal cancer: a retrospective analysis of 104 cases. Cancers 2019; 11:717.
Peretti G, Piazza C, Cocco D, et al. Transoral CO2 laser treatment for Tis-T3 glottic cancer: The University of Brescia experience on 595 patients. Head Neck 2009; 32:977–983.
Marchi F, Piazza C, Ravanelli M, et al. Role of imaging in the follow-up of T2–T3 glottic cancer treated by transoral laser microsurgery. Eur Arch Oto-Rhino-Laryngol 2017; 274:3679–3686.
Vilaseca I, Bernal-Sprekelsen M, Him R, et al. Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer. Eur Arch Oto-Rhino-Laryngol 2015; 272:1203–1210.
Olthoff A, Ewen A, Wolff HA, et al. Organ function and quality of life after transoral laser microsurgery and adjuvant radiotherapy for locally advanced laryngeal cancer. Strahlentherapie Onkol 2009; 185:303–309.
Al-Gilani M, Andrew Skillington S, Kallogjeri D, et al. Surgical vs Nonsurgical treatment modalities for T3 glottic squamous cell carcinoma. JAMA Otolaryngol - Head Neck Surg 2016; 142:940–946.
Hinni ML, Salassa JR, Grant DG, et al. Transoral laser microsurgery for advanced laryngeal cancer. Arch Otolaryngol Neck Surg 2007; 133:1198.
Day AT, Sinha P, Nussenbaum B, et al. Management of primary T1-T4 glottic squamous cell carcinoma by transoral laser microsurgery. Laryngoscope 2017; 127:597–604.
Timmermans AJ, De Gooijer CJ, Hamming-Vrieze O, et al. T3–T4 laryngeal cancer in the Netherlands Cancer Institute; 10-year results of the consistent application of an organ-preserving/-sacrificing protocol. Head Neck 2015; 37:1495–1503.
Vilaseca I, Bernal-Sprekelsen M, Luis Blanch J. Transoral laser microsurgery for T3 laryngeal tumors: prognostic factors. Head Neck 2009; 32:929–938.
Canis M, Ihler F, Martin A, et al. Results of 226 patients with T3 laryngeal carcinoma after treatment with transoral laser microsurgery. Head Neck 2014; 36:652–659.
Butler A, Rigby MH, Scott J, et al. A retrospective review in the management of T3 laryngeal squamous cell carcinoma: an expanding indication for transoral laser microsurgery. J Otolaryngol - Head Neck Surg 2016; 45:
Mannelli G, Lazio MS, Luparello P, Gallo O. Conservative treatment for advanced T3–T4 laryngeal cancer: meta-analysis of key oncological outcomes. Eur Arch Oto-Rhino-Laryngol 2018; 275:27–38.