Bioengineering for head and neck reconstruction: the role of customized flaps.


Journal

Current opinion in otolaryngology & head and neck surgery
ISSN: 1531-6998
Titre abrégé: Curr Opin Otolaryngol Head Neck Surg
Pays: United States
ID NLM: 9417024

Informations de publication

Date de publication:
01 Apr 2021
Historique:
entrez: 5 3 2021
pubmed: 6 3 2021
medline: 26 10 2021
Statut: ppublish

Résumé

The purpose of this review is to provide the reader with an overview of the present and future applications of bioengineering for head and neck reconstruction, ranging from the application of Computed Assisted Surgery (CAS) to the most recent advances in 3D printing and tissue engineering. The use of CAS in head and neck reconstruction has been demonstrated to provide shorter surgical times, improved reconstructive accuracy of bone reconstruction, and achieves better alignment of bone segments in osteotomized reconstructions. Beyond its classical application in bone reconstructions, CAS has demonstrated reliability in the planning and harvesting of soft tissue flaps. To date, literature regarding bioengineering for head and neck reconstruction is mainly focused on in-vitro and animal model experiments; however, some pioneering reports on human patients suggest the potential feasibility of this technology. Bioengineering is anticipated to play a key role in the future development of customized flaps for head and neck reconstruction. These technologies are particularly appealing as a new technology to address certain unsolved challenges in head and neck reconstruction.

Identifiants

pubmed: 33664198
doi: 10.1097/MOO.0000000000000705
pii: 00020840-202104000-00014
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

156-160

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Références

Liu J, Shi Q, Yang S, et al. Does postoperative anticoagulation therapy lead to a higher success rate for microvascular free-tissue transfer in the head and neck? A systematic review and meta-analysis. J Reconstr Microsurg 2018; 34:87–94.
Kruse ALD, Luebbers HT, Grätz KW, Obwegeser JA. Factors influencing survival of free-flap in reconstruction for cancer of the head and neck: a literature review. Microsurgery 2010; 30:242–248.
Varvares MA, Lin D, Hadlock T, et al. Success of multiple, sequential, free tissue transfers to the head and neck. Laryngoscope 2005; 115:101–104.
Tarsitano A, Ciocca L, Scotti R, Marchetti C. Morphological results of customized microvascular mandibular reconstruction: a comparative study. J Craniomaxillofac Surg 2016; 44:697–702.
Chang EI, Jenkins MP, Patel SA, Topham NS. Long-term operative outcomes of preoperative computed tomography-guided virtual surgical planning for osteocutaneous free flap mandible reconstruction. Plast Reconstr Surg 2016; 137:619–623.
Rendenbach C, Steffen C, Hanken H, et al. Complication rates and clinical outcomes of osseous free flaps: a retrospective comparison of CAD/CAM versus conventional fixation in 128 patients. Int J Oral Maxillofac Surg 2019; 48:1156–1162.
Weitz J, Bauer FJM, Hapfelmeier A, et al. Accuracy of mandibular reconstruction by three-dimensional guided vascularised fibular free flap after segmental mandibulectomy. Br J Oral Maxillofac Surg 2016; 54:506–510.
Ritschl LM, Mücke T, Fichter A, et al. Functional outcome of CAD/CAM-assisted versus conventional microvascular, fibular free flap reconstruction of the mandible: a retrospective study of 30 cases. J Reconstr Microsurg 2017; 33:281–291.
Yang W-F, Choi WS, Wong MC-M, et al. Three-dimensionally printed patient-specific surgical plates increase accuracy of oncologic head and neck reconstruction versus conventional surgical plates: a comparative study. Ann Surg Oncol 2021; 28:363–375.
Kass JI, Prisman E, Miles BA. Guide design in virtual planning for scapular tip free flap reconstruction. Laryngoscope Investig Otolaryngol 2018; 3:162–168.
Voss PJ, Steybe D, Fuessinger MA, et al. Vascularized scapula and latissimus dorsi flap for CAD/CAM assisted reconstruction of mandibular defects including the mandibular condyle: technical report and clinical results. BMC Surg 2019; 19:67.
Koumoullis H, Burley O, Kyzas P. Patient-specific soft tissue reconstruction: an IDEAL stage I report of hemiglossectomy reconstruction and introduction of the PANSOFOS flap. Br J Oral Maxillofac Surg 2020; 58:681–686.
Roffi A, Krishnakumar GS, Gostynska N, et al. The role of three-dimensional scaffolds in treating long bone defects: evidence from preclinical and clinical literature-a systematic review. Biomed Res Int 2017; 2017:8074178.
Motamedian SR, Hosseinpour S, Ahsaie MG, Khojasteh A. Smart scaffolds in bone tissue engineering: a systematic review of literature. World J Stem Cells 2015; 7:657–668.
Warnke PH, Springer ING, Wiltfang J, et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 2004; 364:766–770.
Warnke PH, Wiltfang J, Springer I, et al. Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. Biomaterials 2006; 27:3163–3167.
Heliotis M, Lavery KM, Ripamonti U, et al. Transformation of a prefabricated hydroxyapatite/osteogenic protein-1 implant into a vascularised pedicled bone flap in the human chest. Int J Oral Maxillofac Surg 2006; 35:265–269.
Sándor GK, Tuovinen VJ, Wolff J, et al. Adipose stem cell tissue-engineered construct used to treat large anterior mandibular defect: a case report and review of the clinical application of good manufacturing practice-level adipose stem cells for bone regeneration. J Oral Maxillofac Surg 2013; 71:938–950.
Wiltfang J, Rohnen M, Egberts J-H, et al. Man as a living bioreactor: prefabrication of a custom vascularized bone graft in the gastrocolic omentum. Tissue Eng Part C Methods 2016; 22:740–746.
Cao Y, Vacanti JP, Paige KT, et al. Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human ear. Plast Reconstr Surg 1997; 100:297–302.
Fulco I, Miot S, Haug MD, et al. Engineered autologous cartilage tissue for nasal reconstruction after tumour resection: an observational first-in-human trial. Lancet 2014; 384:337–346.
Yanaga H, Imai K, Fujimoto T, Yanaga K. Generating ears from cultured autologous auricular chondrocytes by using two-stage implantation in treatment of microtia. Plast Reconstr Surg 2009; 124:817–825.
Xu Y, Fan F, Kang N, et al. Tissue engineering of human nasal alar cartilage precisely by using three-dimensional printing. Plast Reconstr Surg 2015; 135:451–458.
Park JH, Park JY, Nam I-C. A rational tissue engineering strategy based on three-dimensional (3D) printing for extensive circumferential tracheal reconstruction. Biomaterials 2018; 185:276–283.
Bae S-W, Lee K-W, Park J-H, et al. 3D bioprinted artificial trachea with epithelial cells and chondrogenic-differentiated bone marrow-derived mesenchymal stem cells. Int J Mol Sci 2018; 19:
Zhang H, Fu W, Xu Z. Re-epithelialization: a key element in tracheal tissue engineering. Regen Med 2015; 10:1005–1023.
Hamilton N, Bullock AJ, Macneil S, et al. Tissue engineering airway mucosa: a systematic review. Laryngoscope 2014; 124:961–968.
Soleas JP, Paz A, Marcus P, et al. Engineering airway epithelium. J Biomed Biotechnol 2012; 2012:982971.
Goh CS-L, Joethy J-V, Tan B-K, Wong M. Large animal models for long-segment tracheal reconstruction: a systematic review. J Surg Res 2018; 231:140–153.
Law JX, Liau LL, Aminuddin BS, Ruszymah BHI. Tissue-engineered trachea: a review. Int J Pediatr Otorhinolaryngol 2016; 91:55–63.
Jung H-M, Lee J-E, Lee S-J, et al. Development of an experimental model for radiation-induced inhibition of cranial bone regeneration. Maxillofac Plast Reconstr Surg 2018; 40:34.

Auteurs

Tommaso Gualtieri (T)

Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia - ASST 'Spedali Civili di Brescia', Brescia, Italy.
Department of Otolaryngology - Head and Neck Surgery/Surgical Oncology, Princess Margaret Cancer Centre/University Health Network.
Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada.

Stefano Taboni (S)

Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada.
Section of Otorhinolaryngology - Head and Neck Surgery, University of Padua - Azienda Ospedaliera di Padova, Padova.
Artificial Intelligence in Medicine and Innovation in Clinical Research and Methodology (PhD program), Department of Clinical and Experimental Sciences.

Marco Ferrari (M)

Guided Therapeutics (GTx) Program, Techna Institute, University Health Network, Toronto, Ontario, Canada.
Section of Otorhinolaryngology - Head and Neck Surgery, University of Padua - Azienda Ospedaliera di Padova, Padova.
Technology for Health (PhD program), Department of Information Engineering, University of Brescia, Brescia, Italy.

Ralph Gilbert (R)

Department of Otolaryngology - Head and Neck Surgery/Surgical Oncology, Princess Margaret Cancer Centre/University Health Network.

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