A community perspective on the concept of marine holobionts: current status, challenges, and future directions.
Dysbiosis
Ecosystem services
Evolution
Host-microbiota interactions
Marine holobionts
Symbiosis
Journal
PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425
Informations de publication
Date de publication:
2021
2021
Historique:
received:
06
10
2020
accepted:
16
01
2021
entrez:
5
3
2021
pubmed:
6
3
2021
medline:
6
3
2021
Statut:
epublish
Résumé
Host-microbe interactions play crucial roles in marine ecosystems. However, we still have very little understanding of the mechanisms that govern these relationships, the evolutionary processes that shape them, and their ecological consequences. The holobiont concept is a renewed paradigm in biology that can help to describe and understand these complex systems. It posits that a host and its associated microbiota with which it interacts, form a holobiont, and have to be studied together as a coherent biological and functional unit to understand its biology, ecology, and evolution. Here we discuss critical concepts and opportunities in marine holobiont research and identify key challenges in the field. We highlight the potential economic, sociological, and environmental impacts of the holobiont concept in marine biological, evolutionary, and environmental sciences. Given the connectivity and the unexplored biodiversity specific to marine ecosystems, a deeper understanding of such complex systems requires further technological and conceptual advances, e.g., the development of controlled experimental model systems for holobionts from all major lineages and the modeling of (info)chemical-mediated interactions between organisms. Here we propose that one significant challenge is to bridge cross-disciplinary research on tractable model systems in order to address key ecological and evolutionary questions. This first step is crucial to decipher the main drivers of the dynamics and evolution of holobionts and to account for the holobiont concept in applied areas, such as the conservation, management, and exploitation of marine ecosystems and resources, where practical solutions to predict and mitigate the impact of human activities are more important than ever.
Identifiants
pubmed: 33665032
doi: 10.7717/peerj.10911
pii: 10911
pmc: PMC7916533
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e10911Subventions
Organisme : NCIPC CDC HHS
ID : U17 CE002001
Pays : United States
Informations de copyright
©2021 Dittami et al.
Déclaration de conflit d'intérêts
Fabrice Not is currently a PeerJ Academic Editor. Monica Medina is a former PeerJ Academic Editor.
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