Core prescription pattern of Chinese herbal medicine for depressive disorders in Taiwan: a nationwide population-based study.
Chinese herbal medicine
Depressive disorders
National health insurance research database
Traditional chinese medicine
Journal
Integrative medicine research
ISSN: 2213-4220
Titre abrégé: Integr Med Res
Pays: Netherlands
ID NLM: 101612707
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
07
09
2020
revised:
10
11
2020
accepted:
27
11
2020
entrez:
5
3
2021
pubmed:
6
3
2021
medline:
6
3
2021
Statut:
ppublish
Résumé
Depressive disorders (DD) affect not only mood and behavior but also various physical functions. Traditional Chinese medicine (TCM) has been shown to have some benefits in treating DD. However, one formula or one single herb might be not show high efficacy when used to treat depression. Thus, this study aimed to examine the core prescription pattern of Chinese herbal medicine (CHM) among patients with DD in Taiwan as a reference for related research and clinical applications. All patients, who had been diagnosed with major depressive disorder or minor depression or dysthymia without any other baseline diseases and had at least one CHM outpatient clinical visit from 2002 to 2011, were extracted from three randomly sampled cohorts, namely the 2000, 2005 and 2010 cohorts of the National Health Insurance Research Database (NHIRD) of Taiwan. The collected data was analyzed to explore the patterns of herbal products. There were 197,146 patients with a diagnosis of DD and of these 1806 subjects had only a diagnosis of DD and utilized CHM. The most common formula was This study describes the CHM core prescription pattern used to treat patients in Taiwan with DD and it is a potential candidate for study in future pharmacological or clinical trials targeting DD.
Sections du résumé
BACKGROUND
BACKGROUND
Depressive disorders (DD) affect not only mood and behavior but also various physical functions. Traditional Chinese medicine (TCM) has been shown to have some benefits in treating DD. However, one formula or one single herb might be not show high efficacy when used to treat depression. Thus, this study aimed to examine the core prescription pattern of Chinese herbal medicine (CHM) among patients with DD in Taiwan as a reference for related research and clinical applications.
METHODS
METHODS
All patients, who had been diagnosed with major depressive disorder or minor depression or dysthymia without any other baseline diseases and had at least one CHM outpatient clinical visit from 2002 to 2011, were extracted from three randomly sampled cohorts, namely the 2000, 2005 and 2010 cohorts of the National Health Insurance Research Database (NHIRD) of Taiwan. The collected data was analyzed to explore the patterns of herbal products.
RESULTS
RESULTS
There were 197,146 patients with a diagnosis of DD and of these 1806 subjects had only a diagnosis of DD and utilized CHM. The most common formula was
CONCLUSIONS
CONCLUSIONS
This study describes the CHM core prescription pattern used to treat patients in Taiwan with DD and it is a potential candidate for study in future pharmacological or clinical trials targeting DD.
Identifiants
pubmed: 33665095
doi: 10.1016/j.imr.2020.100707
pii: S2213-4220(20)30344-9
pmc: PMC7903348
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100707Informations de copyright
© 2021 Published by Elsevier B.V. on behalf of Korea Institute of Oriental Medicine.
Références
BMC Health Serv Res. 2007 Feb 23;7:26
pubmed: 17319950
J Obstet Gynaecol Res. 2013 Jan;39(1):223-8
pubmed: 22765925
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1;32(3):881-5
pubmed: 18243460
J Ethnopharmacol. 1986 Sep;17(3):257-61
pubmed: 2433549
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Dec 2;47:33-9
pubmed: 23876788
Complement Ther Med. 2013 Jun;21(3):215-23
pubmed: 23642954
J Ethnopharmacol. 2010 Jul 6;130(1):163-6
pubmed: 20347951
Pharm Biol. 2010 Dec;48(12):1328-36
pubmed: 20738212
J Chin Med Assoc. 2020 Oct;83(10):967-971
pubmed: 32649417
J Acupunct Meridian Stud. 2013 Feb;6(1):2-11
pubmed: 23433049
Zhong Yao Cai. 2001 Jan;24(1):40-1
pubmed: 11341029
J Psychiatr Res. 2014 Oct;57:165-75
pubmed: 24974002
Life Sci. 2001 Sep 21;69(18):2167-77
pubmed: 11669460
J Affect Disord. 2017 Jan 01;207:188-196
pubmed: 27723543
Molecules. 2017 Dec 18;22(12):
pubmed: 29258229
East Asian Arch Psychiatry. 2012 Dec;22(4):146-53
pubmed: 23271583
Biol Pharm Bull. 2006 May;29(5):938-44
pubmed: 16651723
Curr Med Res Opin. 2006 Aug;22(8):1587-97
pubmed: 16870083
Biol Pharm Bull. 1995 Apr;18(4):563-5
pubmed: 7655428
Sci Rep. 2015 Apr 29;5:9541
pubmed: 25923413
Eur J Pharmacol. 2013 Dec 5;721(1-3):267-76
pubmed: 24076326
Behav Brain Res. 2014 Sep 1;271:116-21
pubmed: 24914461
Pharmacol Biochem Behav. 2003 May;75(2):419-25
pubmed: 12873634
Scand J Gastroenterol. 2002 Mar;37(3):294-8
pubmed: 11916191
CMAJ. 2009 Feb 3;180(3):305-13
pubmed: 19188629
J Ethnopharmacol. 2014 Apr 28;153(2):309-17
pubmed: 24632021
PLoS One. 2016 Mar 08;11(3):e0151147
pubmed: 26954017
Arch Gynecol Obstet. 2011 Oct;284(4):913-21
pubmed: 21120510
Phytomedicine. 2010 Jan;17(1):75-80
pubmed: 19682877
Chin J Integr Med. 2017 May;23(5):386-395
pubmed: 26453561
Lancet. 2017 Sep 16;390(10100):1211-1259
pubmed: 28919117
J Ethnopharmacol. 2010 Oct 28;132(1):70-4
pubmed: 20673844
Pharmacol Biochem Behav. 2007 May;87(1):41-7
pubmed: 17477962
Psychiatry Clin Neurosci. 2007 Aug;61(4):401-6
pubmed: 17610665
J Pharm Biomed Anal. 2016 Sep 5;128:469-479
pubmed: 27371920
Hua Xi Yi Ke Da Xue Xue Bao. 1996 Dec;27(4):418-21
pubmed: 9389017
Zhongguo Zhong Yao Za Zhi. 2002 Nov;27(11):862-6
pubmed: 12776593
Evid Based Complement Alternat Med. 2011;2011:673813
pubmed: 21660310
World J Gastroenterol. 2005 May 7;11(17):2670-3
pubmed: 15849832
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jan 1;32(1):150-4
pubmed: 17765378
Prim Care Companion CNS Disord. 2013;15(2):
pubmed: 23930236
Hua Xi Yi Ke Da Xue Xue Bao. 1990 Jun;21(2):175-7
pubmed: 2391099
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Dec;26(12):1114-6
pubmed: 17205825
Biol Pharm Bull. 2004 Aug;27(8):1317-9
pubmed: 15305046
J Tradit Complement Med. 2017 Mar 03;8(1):53-59
pubmed: 29321989
J Tradit Chin Med. 1999 Dec;19(4):296-7
pubmed: 10921137
Chin Med. 2016 Apr 29;11:21
pubmed: 27134643
J Ethnopharmacol. 2017 Jan 20;196:1-8
pubmed: 27965049
Pharm Biol. 2010 Jul;48(7):801-7
pubmed: 20645780
J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 1;1086:29-37
pubmed: 29654984
Psychiatry Clin Neurosci. 2007 Jun;61(3):323-5
pubmed: 17472603
Hong Kong Med J. 2001 Dec;7(4):392-402
pubmed: 11773674
J Ethnopharmacol. 2015 Aug 2;171:307-16
pubmed: 26068429
J Pharm Pharmacol. 2000 Nov;52(11):1425-9
pubmed: 11186252
Pharm Biol. 2015 Aug;53(8):1168-75
pubmed: 25857699
J Ethnopharmacol. 2012 Sep 28;143(2):533-9
pubmed: 22819689
Life Sci. 2004 Oct 22;75(23):2787-95
pubmed: 15464830
J Ethnopharmacol. 1986 Mar;15(3):289-96
pubmed: 3724209
BMC Complement Altern Med. 2016 Jul 15;16:219
pubmed: 27422559
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 May;31(5):618-21
pubmed: 21812260
Pharmacol Biochem Behav. 2009 Mar;92(1):39-43
pubmed: 19000708
Medicine (Baltimore). 2016 Jul;95(27):e4115
pubmed: 27399116
Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(2):217-23
pubmed: 19385190
Acta Pharmacol Sin. 2016 Aug;37(8):1045-53
pubmed: 27180981
Molecules. 2017 Aug 11;22(8):
pubmed: 28800105
Pharmacol Biochem Behav. 2009 Apr;92(2):206-13
pubmed: 19101585
PLoS One. 2014 Feb 10;9(2):e88617
pubmed: 24520403
Psychiatr Serv. 2015 Nov;66(11):1245-8
pubmed: 26073413
Zhongguo Zhong Yao Za Zhi. 2016 Apr;41(8):1511-1515
pubmed: 28884548
Br J Psychiatry. 2009 Sep;195(3):202-10
pubmed: 19721108
Evid Based Complement Alternat Med. 2012;2012:940846
pubmed: 23008744
Life Sci. 2002 Nov 22;72(1):67-77
pubmed: 12409146