Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft.

Tissue-engineered vascular grafts endothelial heterogeneity scaffold materials seed cells vascular endothelialization

Journal

Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 21 10 2020
revised: 09 12 2020
accepted: 21 12 2020
entrez: 5 3 2021
pubmed: 6 3 2021
medline: 6 3 2021
Statut: epublish

Résumé

Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs (<6 mm) after transplantation. Endothelialization of TEVGs is a key point to prevent thrombosis. Here, we discuss different types of endothelialization and different seed cells of tissue-engineered vascular grafts. Meanwhile, endothelial heterogeneity is also discussed. Based on it, we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths.

Identifiants

pubmed: 33665496
doi: 10.1016/j.bioactmat.2020.12.021
pii: S2452-199X(20)30346-7
pmc: PMC7887299
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

2557-2568

Informations de copyright

© 2021 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

Déclaration de conflit d'intérêts

Authors do not have any conflicts of interest to declare.

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Auteurs

Qingjin Cai (Q)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.

Wanshan Liao (W)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.

Fangchao Xue (F)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.

Xiaochen Wang (X)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.

Weiming Zhou (W)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.

Yanzhao Li (Y)

State Key Laboratory of Trauma, Burn and Combined Injury, Chongqing, China.

Wen Zeng (W)

Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.
State Key Laboratory of Trauma, Burn and Combined Injury, Chongqing, China.
Departments of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China.

Classifications MeSH