Immunization with
Brugia malayi
calreticulin
immunization
microfilariae
parasite burden
Journal
ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580
Informations de publication
Date de publication:
09 04 2021
09 04 2021
Historique:
pubmed:
6
3
2021
medline:
24
6
2021
entrez:
5
3
2021
Statut:
ppublish
Résumé
Lymphatic filariasis causes permanent and long-term disability worldwide. Lack of potent adulticidal drugs, the emergence of drug resistance, and the nonavailability of effective vaccines are the major drawbacks toward LF elimination. However, immunomodulatory proteins present in the parasite secretome are capable of providing good protection against LF and thus offer hope in designing new vaccines against LF. Here, we evaluated the immunogenicity and protective efficacy of
Identifiants
pubmed: 33667079
doi: 10.1021/acsinfecdis.0c00565
doi:
Substances chimiques
Antiparasitic Agents
0
Calreticulin
0
Cytokines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM