Prevalence and determinants of restless leg syndrome in type 2 diabetes mellitus (T2DM) in Pakistan.


Journal

Diabetes & metabolic syndrome
ISSN: 1878-0334
Titre abrégé: Diabetes Metab Syndr
Pays: Netherlands
ID NLM: 101462250

Informations de publication

Date de publication:
Historique:
received: 23 12 2020
revised: 04 02 2021
accepted: 06 02 2021
pubmed: 6 3 2021
medline: 12 11 2021
entrez: 5 3 2021
Statut: ppublish

Résumé

Restless legs syndromes (RLS) are intrinsic sleeping disorder and its prevalence rate is 10-15% in general population but it is observed that prevalence rate is different in diabetes patients. Current study aims to find prevalence and determinants of RLS in people living with type 2 diabetes mellitus in Pakistan. A multicenter cross-sectional observational study was conducted in 388 diabetes patients attending daily diabetes clinics and teaching hospitals in Pakistan's twin city between August 2019 and February 2020. The chi-square test and linear regression were used to detect RLS-related factors in type 2 diabetes mellitus. The prevalence of RLS found was; 3.1% patients with diabetes were suffering from very severe RLS, 23.5% from severe RLS, 34% from moderate RLS, 21.1% from mild RLS and 18.3% from non-RLS. Gender, age, education, blood glucose fasting (BSF), blood glucose random (BSR) and HBA1c were found to be significant predictors of RLS in patients with diabetes. Policy makers can develop local interventions to curb the growing RLS prevalence by keeping in control the risk factors of RLS in people living with type 2 diabetes.

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
Restless legs syndromes (RLS) are intrinsic sleeping disorder and its prevalence rate is 10-15% in general population but it is observed that prevalence rate is different in diabetes patients. Current study aims to find prevalence and determinants of RLS in people living with type 2 diabetes mellitus in Pakistan.
METHOD METHODS
A multicenter cross-sectional observational study was conducted in 388 diabetes patients attending daily diabetes clinics and teaching hospitals in Pakistan's twin city between August 2019 and February 2020. The chi-square test and linear regression were used to detect RLS-related factors in type 2 diabetes mellitus.
RESULTS RESULTS
The prevalence of RLS found was; 3.1% patients with diabetes were suffering from very severe RLS, 23.5% from severe RLS, 34% from moderate RLS, 21.1% from mild RLS and 18.3% from non-RLS. Gender, age, education, blood glucose fasting (BSF), blood glucose random (BSR) and HBA1c were found to be significant predictors of RLS in patients with diabetes.
CONCLUSION CONCLUSIONS
Policy makers can develop local interventions to curb the growing RLS prevalence by keeping in control the risk factors of RLS in people living with type 2 diabetes.

Identifiants

pubmed: 33668002
pii: S1871-4021(21)00036-9
doi: 10.1016/j.dsx.2021.02.013
pii:
doi:

Substances chimiques

Blood Glucose 0

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

525-528

Informations de copyright

Copyright © 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest Authors has no conflict of interest.

Auteurs

Muhammad Shahzad Nawaz (MS)

Department of Pharmacy, Punjab University College of Pharmacy, AllamaIqbal Campus, University of the Punjab, 54000, Lahore, Pakistan. Electronic address: msnawaz@bs.qau.edu.pk.

Muhammad Sarfraz Nawaz (MS)

Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan.

Kifayat-Ullah Shah (KU)

Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan.

Zia Ul Mustafa (ZU)

District Head Quarter (DHQ) Hospital, Pakpattan and Punjab University Lahore, Pakistan.

Ali Ahmed (A)

School of Pharmacy, Monash University, Jalan Lagoon Selatan, 47500, Bandar Sunway Selangor DarulEhsan, Malaysia.

Hafiz Sajjad Ahmed (H)

Capital Authority Hospital Islamabad, Pakistan.

Tahir Mehmood Khan (TM)

School of Pharmacy, Monash University, Jalan Lagoon Selatan, 47500, Bandar Sunway Selangor DarulEhsan, Malaysia.

Allah Bukhsh (A)

Institute of Pharmaceutical Sciences, University of Veterinary and Animal Science, Lahore, Pakistan.

Salamat Ali (S)

Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan.

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