Choroidal Vascularity Features in Patients with Choroideremia and Cystoid Spaces.

choroidal vascularity index choroideremia cystoid macular edema cystoid space.

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
24 Feb 2021
Historique:
received: 02 02 2021
revised: 20 02 2021
accepted: 21 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 7 3 2021
Statut: epublish

Résumé

Cystoid spaces (CSs) are a common retinal finding in choroideremia (CHM) patients. The aim of this study was to analyze the vascular features of the choroid associated with the presence of CSs in patients with confirmed genetic diagnosis of CHM. A total of 33 patients (33 eyes) were enrolled in this retrospective cross-sectional study and divided into two groups based on the presence (17 eyes) or absence (16 eyes) of CSs. Choroidal features were evaluated on spectral-domain optical coherence tomography including subfoveal choroidal thickness (CT), total choroidal area (TCA), luminal choroidal area (LCA), and stromal choroidal area (SCA). The choroidal vascularity index (CVI) was then calculated in all study eyes. All structural choroidal parameters were calculated both on the entire length of the B-scan and in the central subfoveal 1500 μm. The average age was 37.3 ± 11.6 and 31.4 ± 16.7 years (

Identifiants

pubmed: 33668232
pii: diagnostics11030382
doi: 10.3390/diagnostics11030382
pmc: PMC7996232
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Claudio Iovino (C)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Valentina Di Iorio (V)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Francesco Testa (F)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Viviana Bombace (V)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Paolo Melillo (P)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Kiran Kumar Vupparaboina (KK)

Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad 500034, India.

Jay Chhablani (J)

Department of Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

Francesca Simonelli (F)

Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', via Pansini 5, 80131 Naples, Italy.

Classifications MeSH