Cocaine Induces Cytoskeletal Changes in Cardiac Myocytes: Implications for Cardiac Morphology.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
24 Feb 2021
Historique:
received: 16 01 2021
revised: 17 02 2021
accepted: 18 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 30 4 2021
Statut: epublish

Résumé

Cocaine is one of the most widely abused illicit drugs worldwide and has long been recognised as an agent of cardiac dysfunction in numerous cases of drug overdose. Cocaine has previously been shown to up-regulate cytoskeletal rearrangements and morphological changes in numerous tissues; however, previous literature observes such changes primarily in clinical case reports and addiction studies. An investigation into the fundamental cytoskeletal parameters of migration, adhesion and proliferation were studied to determine the cytoskeletal and cytotoxic basis of cocaine in cardiac cells. Treatment of cardiac myocytes with cocaine increased cell migration and adhesion (

Identifiants

pubmed: 33668403
pii: ijms22052263
doi: 10.3390/ijms22052263
pmc: PMC7956613
pii:
doi:

Substances chimiques

Vasoconstrictor Agents 0
Cocaine I5Y540LHVR

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Cardiovasc Toxicol. 2008 Dec;8(4):161-71
pubmed: 18813882
Neuron. 2017 Dec 20;96(6):1327-1341.e6
pubmed: 29268097
J Am Coll Cardiol. 2017 Jul 4;70(1):101-113
pubmed: 28662796
Mol Cell Biol. 2006 May;26(9):3432-45
pubmed: 16611986
Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1697-710
pubmed: 19734360
PLoS One. 2017 Dec 5;12(12):e0189139
pubmed: 29206857
Development. 2012 Nov;139(22):4133-42
pubmed: 23034636
Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26460-26469
pubmed: 33020308
Asian J Androl. 2017 Jan-Feb;19(1):67-72
pubmed: 27678468
Toxicol In Vitro. 1988;2(3):205-13
pubmed: 20702336
PLoS One. 2015 Jan 24;10(1):e0114285
pubmed: 25617894
Respir Res. 2018 Nov 21;19(1):229
pubmed: 30463566
J Sex Med. 2015 Jul;12(7):1522-32
pubmed: 25923835
J Neurosci. 2006 Feb 1;26(5):1579-87
pubmed: 16452681
J Mol Med (Berl). 2014 Jan;92(1):43-51
pubmed: 24292258
J Neurosci. 2019 Jul 17;39(29):5634-5646
pubmed: 31092585
Neuroscience. 2011 Nov 24;196:1-15
pubmed: 21925237
Atherosclerosis. 2017 Jul;262:154-162
pubmed: 28363516
Neuroscience. 2009 Oct 6;163(2):501-5
pubmed: 19580848
J Biol Chem. 2007 Nov 2;282(44):32520-8
pubmed: 17848544
J Cardiovasc Magn Reson. 2014 Apr 23;16:26
pubmed: 24758161
Am J Public Health. 2017 Mar;107(3):430-432
pubmed: 28177817
Eur Heart J. 2011 May;32(10):1244-50
pubmed: 21266375
J Neurosci. 2011 Apr 20;31(16):5942-55
pubmed: 21508219
Mol Cell. 2011 Mar 18;41(6):661-71
pubmed: 21419341
Biochim Biophys Acta. 2008 Sep;1782(9):542-8
pubmed: 18606220
Eur Heart J Case Rep. 2018 Apr 17;2(2):yty041
pubmed: 31020121
F1000Prime Rep. 2015 Jan 14;7:08
pubmed: 25705391
Can J Physiol Pharmacol. 2010 Mar;88(3):324-30
pubmed: 20393597
J Clin Invest. 2013 Oct;123(10):4294-308
pubmed: 24091324
J Pharmacol Exp Ther. 2000 Jan;292(1):8-14
pubmed: 10604926
J Biol Chem. 2003 Apr 11;278(15):13016-25
pubmed: 12571246
J Am Coll Cardiol. 2006 May 16;47(10):2120-2
pubmed: 16697335
Arch Med Sci. 2019 Dec 31;16(1):66-70
pubmed: 32051707
Sci Rep. 2017 Mar 08;7:43658
pubmed: 28272550
J Anal Toxicol. 2014 Jan-Feb;38(1):46-51
pubmed: 24327622
Oxid Med Cell Longev. 2017;2017:3034245
pubmed: 28593024
Cardiovasc Toxicol. 2005 Fall;5(4):377-90
pubmed: 16382175
Mol Med Rep. 2017 Nov;16(5):6634-6641
pubmed: 28901418
Basic Clin Pharmacol Toxicol. 2006 May;98(5):510-7
pubmed: 16635111
Curr Med Chem. 2012;19(33):5619-23
pubmed: 22856662
Cell Adh Migr. 2011 Mar-Apr;5(2):199-206
pubmed: 21343695
J Physiol. 2017 Apr 1;595(7):2299-2300
pubmed: 28028806
J Am Coll Cardiol. 2018 Feb 27;71(8):952-954
pubmed: 29471945
Drug Alcohol Depend. 2016 Jan 1;158:181-5
pubmed: 26679059
Int J Mol Sci. 2019 Jan 29;20(3):
pubmed: 30700023
Cell Death Discov. 2018 Jul 17;4:13
pubmed: 30210816
Am J Pathol. 2014 Apr;184(4):927-936
pubmed: 24486327
Cell Adh Migr. 2007 Oct-Dec;1(4):171-5
pubmed: 19262139
Am J Physiol Cell Physiol. 2009 Mar;296(3):C453-62
pubmed: 19118163
Drug Test Anal. 2017 Jan;9(1):106-114
pubmed: 26888521
Cytotechnology. 2016 Dec;68(6):2407-2415
pubmed: 26946144
Circulation. 1999 Jun 1;99(21):2737-41
pubmed: 10351966
Forensic Sci Int. 2018 Apr;285:86-92
pubmed: 29454838
Apoptosis. 2011 Jun;16(6):563-73
pubmed: 21424555
Postgrad Med J. 2005 Dec;81(962):741-5
pubmed: 16344295
Int J Cardiol Heart Vasc. 2015 Mar 06;7:131-140
pubmed: 28785661
Arch Toxicol. 2018 Jul;92(7):2311-2325
pubmed: 29846769
J Pharmacol Exp Ther. 2009 Jan;328(1):99-106
pubmed: 18952886
Sci Rep. 2017 Feb 22;7:43146
pubmed: 28225063
Forensic Sci Int. 1990 Dec;48(2):135-8
pubmed: 2283136
Cell Adh Migr. 2014;8(5):440-51
pubmed: 25482647

Auteurs

Avnish Verma (A)

Cardiovascular Science, Institute of Life Course and Medical Sciences, Faculty of Health & Life Sciences, University of Liverpool, Liverpool L7 8TX, UK.

Ayse Orme Merve (A)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Vytautas Remeškevičius (V)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Pola Sobiecka (P)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Luke Taylor (L)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Scott Lawton (S)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Ben P Jones (BP)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Elena Polycarpou (E)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

Jason Bennett (J)

Centre for Sport, Exercise and Life Sciences (CSELS), Coventry University, Pharmacology and Therapeutics, Alison Gingell Building, Whitefriars Street, Coventry CV1 2DS, UK.

Brian Rooney (B)

School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, London, KT1 2EE, UK.

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Classifications MeSH