Neutrophil-to-Lymphocyte Ratio Is a Useful Marker for Predicting Histological Types of Early Gastric Cancer.
endoscopic submucosal dissection (ESD)
gastric cancer
neutrophil-to-lymphocyte ratio (NLR)
platelet-to-lymphocyte ratio (PLR)
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 Feb 2021
16 Feb 2021
Historique:
received:
29
01
2021
revised:
11
02
2021
accepted:
15
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
7
3
2021
Statut:
epublish
Résumé
The indications for endoscopic submucosal dissection (ESD) for gastric cancer are based on preoperative histological assessment; however, examination of tissue biopsy is not always reliable as only a limited portion of the lesion can be obtained. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are markers of inflammatory response and are potentially associated with the grade of malignancy in gastric cancer. We aimed to investigate the association between NLR and PLR and the histology of gastric cancer. This study included 218 patients who underwent ESD for gastric cancer. The relationship between NLR/PLR and histological diagnosis was investigated. Patients with adenocarcinomas showed significantly higher NLR and PLR than those with adenomas ( This study suggests that NLR could be a useful marker for assessing early gastric cancer.
Sections du résumé
BACKGROUND
BACKGROUND
The indications for endoscopic submucosal dissection (ESD) for gastric cancer are based on preoperative histological assessment; however, examination of tissue biopsy is not always reliable as only a limited portion of the lesion can be obtained. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are markers of inflammatory response and are potentially associated with the grade of malignancy in gastric cancer. We aimed to investigate the association between NLR and PLR and the histology of gastric cancer.
METHODS
METHODS
This study included 218 patients who underwent ESD for gastric cancer. The relationship between NLR/PLR and histological diagnosis was investigated.
RESULTS
RESULTS
Patients with adenocarcinomas showed significantly higher NLR and PLR than those with adenomas (
CONCLUSION
CONCLUSIONS
This study suggests that NLR could be a useful marker for assessing early gastric cancer.
Identifiants
pubmed: 33669317
pii: jcm10040791
doi: 10.3390/jcm10040791
pmc: PMC7920243
pii:
doi:
Types de publication
Journal Article
Langues
eng
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