Assessment of Appropriateness of Antimicrobial Therapy in Resource-Constrained Settings: Development and Piloting of a Novel Tool-AmRAT.
antimicrobial prescribing
antimicrobial stewardship
appropriateness of antimicrobial therapy
lower- and middle-income countries
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
19 Feb 2021
19 Feb 2021
Historique:
received:
09
01
2021
revised:
25
01
2021
accepted:
27
01
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
7
3
2021
Statut:
epublish
Résumé
Inappropriate antimicrobial prescribing is considered to be the leading cause of high burden of antimicrobial resistance (AMR) in resource-constrained lower- and middle-income countries. Under its global action plan, the World Health Organization has envisaged tackling the AMR threat through promotion of rational antibiotic use among prescribers. Given the lack of consensus definitions and other associated challenges, we sought to devise and validate an Antimicrobial Rationality Assessment Tool-AmRAT-for standardizing the assessment of appropriateness of antimicrobial prescribing. A consensus algorithm was developed by a multidisciplinary team consisting of intensivists, internal medicine practitioners, clinical pharmacologists, and infectious disease experts. The tool was piloted by 10 raters belonging to three groups of antimicrobial stewardship (AMS) personnel: Master of Pharmacology (M.Sc.) (
Identifiants
pubmed: 33669509
pii: antibiotics10020200
doi: 10.3390/antibiotics10020200
pmc: PMC7923130
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Clin Epidemiol. 1990;43(6):543-9
pubmed: 2348207
Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3463-E3470
pubmed: 29581252
Clin Microbiol Infect. 2017 Aug;23(8):524-532
pubmed: 28268133
Clin Infect Dis. 2020 Jun 24;:
pubmed: 32579180
Int J Antimicrob Agents. 2007 Jun;29(6):693-9
pubmed: 17400430
Biometrics. 1977 Mar;33(1):159-74
pubmed: 843571
Front Public Health. 2020 Apr 28;8:140
pubmed: 32411647
Psychiatry Res. 1993 Oct;49(1):97-8
pubmed: 8140185
Infect Dis (Lond). 2019 May;51(5):395-398
pubmed: 30776933
Biochem Med (Zagreb). 2012;22(3):276-82
pubmed: 23092060
PLoS One. 2016 Mar 15;11(3):e0150795
pubmed: 26978263
J Antimicrob Chemother. 2015;70(6):1912-8
pubmed: 25724986
BMC Geriatr. 2020 Jul 9;20(1):237
pubmed: 32646382
Ann Intern Med. 1973 Oct;79(4):555-60
pubmed: 4795880
Lancet Infect Dis. 2021 Jan;21(1):107-115
pubmed: 32717205
Lancet Infect Dis. 2014 Oct;14(10):1001-10
pubmed: 25189351
J Antimicrob Chemother. 2014 Jan;69(1):234-40
pubmed: 23887867
J Antimicrob Chemother. 1992 Nov;30(5):724-7
pubmed: 1493990
J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi3-vi16
pubmed: 29878216
QJM. 2001 Mar;94(3):141-52
pubmed: 11259689
J Antibiot (Tokyo). 2020 Jun;73(6):329-364
pubmed: 32152527
Glob Heart. 2014 Sep;9(3):347-58
pubmed: 25667187
J Antimicrob Chemother. 2007 May;59(5):990-5
pubmed: 17387117
Swiss Med Wkly. 2019 Oct 27;149:w20135
pubmed: 31656037
Clin Infect Dis. 2016 Dec 15;63(12):1639-1644
pubmed: 27682070
J Med Microbiol. 2019 Nov;68(11):1596-1603
pubmed: 31526454
Infect Control Hosp Epidemiol. 2006 Apr;27(4):378-82
pubmed: 16622816
BMC Infect Dis. 2016 Sep 02;16:465
pubmed: 27590053
Fam Med. 2005 May;37(5):360-3
pubmed: 15883903
Lancet. 2016 Jan 9;387(10014):176-87
pubmed: 26603922
BMC Infect Dis. 2015 Jun 30;15:248
pubmed: 26123222
PLoS Med. 2016 Mar 02;13(3):e1001974
pubmed: 26934098
JAMA. 2002 Jun 19;287(23):3133-5
pubmed: 12069678
PLoS One. 2010 Nov 16;5(11):e14011
pubmed: 21103362
Chest. 2009 Nov;136(5):1237-1248
pubmed: 19696123