Antimicrobial Effect and Cytotoxic Evaluation of Mg-Doped Hydroxyapatite Functionalized with Au-Nano Rods.
Anti-Infective Agents
/ pharmacology
Cell Death
/ drug effects
Cell Survival
/ drug effects
Durapatite
/ pharmacology
Escherichia coli
/ drug effects
Gold
/ pharmacology
Humans
Magnesium
/ pharmacology
Microbial Sensitivity Tests
Nanotubes
/ chemistry
Photoelectron Spectroscopy
Staphylococcus aureus
/ drug effects
Tissue Scaffolds
/ chemistry
Au nanoparticles
antibacterial activity
bone tissue engineering
cytotoxicity
hybrid biomaterials
hydroxyapatite
nano-functionalization
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
19 Feb 2021
19 Feb 2021
Historique:
received:
16
01
2021
revised:
07
02
2021
accepted:
16
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
10
4
2021
Statut:
epublish
Résumé
Hydroxyapatite (HA) is the main inorganic mineral that constitutes bone matrix and represents the most used biomaterial for bone regeneration. Over the years, it has been demonstrated that HA exhibits good biocompatibility, osteoconductivity, and osteoinductivity both in vitro and in vivo, and can be prepared by synthetic and natural sources via easy fabrication strategies. However, its low antibacterial property and its fragile nature restricts its usage for bone graft applications. In this study we functionalized a MgHA scaffold with gold nanorods (AuNRs) and evaluated its antibacterial effect against
Identifiants
pubmed: 33669712
pii: molecules26041099
doi: 10.3390/molecules26041099
pmc: PMC7923154
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Gold
7440-57-5
Durapatite
91D9GV0Z28
Magnesium
I38ZP9992A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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