Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers.
PTEN
breast cancer
cancer therapy
circular RNA
long non-coding RNA
lung cancer
microRNA
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
18 02 2021
18 02 2021
Historique:
received:
24
01
2021
revised:
15
02
2021
accepted:
15
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
24
7
2021
Statut:
epublish
Résumé
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size of 19-24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer progression. miRNAs can function as tumor-suppressing or tumor-promoting factors in cancer via regulating molecular pathways. Breast and lung cancers are two malignant thoracic tumors in which the abnormal expression of miRNAs plays a significant role in their development. Phosphatase and tensin homolog (PTEN) is a tumor-suppressor factor that is capable of suppressing the growth, viability, and metastasis of cancer cells via downregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling. PTEN downregulation occurs in lung and breast cancers to promote PI3K/Akt expression, leading to uncontrolled proliferation, metastasis, and their resistance to chemotherapy and radiotherapy. miRNAs as upstream mediators of PTEN can dually induce/inhibit PTEN signaling in affecting the malignant behavior of lung and breast cancer cells. Furthermore, long non-coding RNAs and circular RNAs can regulate the miRNA/PTEN axis in lung and breast cancer cells. It seems that anti-tumor compounds such as baicalein, propofol, and curcumin can induce PTEN upregulation by affecting miRNAs in suppressing breast and lung cancer progression. These topics are discussed in the current review with a focus on molecular pathways.
Identifiants
pubmed: 33670518
pii: biom11020304
doi: 10.3390/biom11020304
pmc: PMC7922700
pii:
doi:
Substances chimiques
MicroRNAs
0
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
PTEN Phosphohydrolase
EC 3.1.3.67
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministry of Education - Singapore
ID : T2EP30120-0042
Références
Front Pharmacol. 2016 Oct 25;7:395
pubmed: 27826244
PLoS One. 2016 Apr 20;11(4):e0153155
pubmed: 27097161
Curr Vasc Pharmacol. 2017;15(6):503-519
pubmed: 28707601
Exp Ther Med. 2020 Mar;19(3):1605-1616
pubmed: 32104211
EMBO Rep. 2016 May;17(5):648-58
pubmed: 27113763
Oncogene. 2018 Mar;37(9):1142-1158
pubmed: 29255248
Cell Death Dis. 2018 Jan 23;9(2):78
pubmed: 29362431
J Clin Lab Anal. 2020 Oct;34(10):e23442
pubmed: 32592206
Cell Death Differ. 2020 Mar;27(3):966-983
pubmed: 31296961
Oncogenesis. 2019 Nov 4;8(11):65
pubmed: 31685806
Life Sci. 2016 Mar 1;148:313-28
pubmed: 26876915
World J Gastroenterol. 2015 Nov 21;21(43):12261-73
pubmed: 26604635
Cancer Lett. 2020 Sep 28;488:18-26
pubmed: 32473243
Kaohsiung J Med Sci. 2019 Nov;35(11):659-671
pubmed: 31332950
Cell Rep. 2019 Dec 24;29(13):4389-4406.e10
pubmed: 31875548
Mol Ther Nucleic Acids. 2020 Mar 6;19:643-653
pubmed: 31951852
Onco Targets Ther. 2019 Dec 24;12:11465-11474
pubmed: 31920335
Biol Rev Camb Philos Soc. 2016 May;91(2):409-28
pubmed: 25631495
Oncol Rep. 2013 Dec;30(6):2897-902
pubmed: 24084898
Yonsei Med J. 2019 Feb;60(2):148-157
pubmed: 30666836
Cancer. 2007 Jun 15;109(12 Suppl):2627-34
pubmed: 17503444
Gene. 2013 Nov 15;531(1):8-14
pubmed: 23994196
Cells. 2019 Sep 30;8(10):
pubmed: 31575017
Mol Cancer. 2019 Dec 9;18(1):179
pubmed: 31815619
Cancer Invest. 2015 May;33(5):165-71
pubmed: 25831148
Thorac Cancer. 2020 Feb;11(2):415-425
pubmed: 31883226
Front Biosci (Landmark Ed). 2019 Jun 1;24:1426-1439
pubmed: 31136988
Mol Cell Biochem. 2016 Nov;422(1-2):61-74
pubmed: 27644194
Mol Biol Rep. 2020 Dec;47(12):9913-9920
pubmed: 33130965
Onco Targets Ther. 2020 Jan 07;13:109-118
pubmed: 32021259
Pathol Res Pract. 2018 May;214(5):700-705
pubmed: 29567332
Onco Targets Ther. 2019 Dec 31;12:11691-11700
pubmed: 32021247
Mol Ther Nucleic Acids. 2020 Jun 5;20:205-216
pubmed: 32179451
Int J Mol Sci. 2018 Sep 29;19(10):
pubmed: 30274259
Mol Cancer. 2004 Mar 11;3:7
pubmed: 15016316
Cancer Lett. 2016 Oct 10;381(1):49-57
pubmed: 27461583
Oncol Lett. 2015 Nov;10(5):2849-2855
pubmed: 26722252
Mol Carcinog. 2020 Apr;59(4):447-461
pubmed: 32096299
Oncol Rep. 2020 May;43(5):1569-1579
pubmed: 32323848
Sci Rep. 2019 Dec 11;9(1):18844
pubmed: 31827114
Biomed Pharmacother. 2018 Sep;105:545-552
pubmed: 29886375
J Biol Chem. 1997 Jan 3;272(1):601-8
pubmed: 8995303
J Cancer. 2011 Feb 07;2:67-75
pubmed: 21326627
Eur Rev Med Pharmacol Sci. 2020 Jul;24(13):7303-7309
pubmed: 32706068
Mol Oncol. 2019 Dec;13(12):2663-2678
pubmed: 31581360
Kaohsiung J Med Sci. 2020 Apr;36(4):244-249
pubmed: 31859425
Am J Physiol Cell Physiol. 2020 Mar 1;318(3):C649-C663
pubmed: 31693399
Cells. 2020 Jul 18;9(7):
pubmed: 32708484
J Transl Med. 2019 Dec 30;17(1):435
pubmed: 31888645
J Ethnopharmacol. 2016 Dec 4;193:255-265
pubmed: 27566197
Mol Ther Nucleic Acids. 2020 Mar 6;19:790-803
pubmed: 31955010
Biochim Biophys Acta. 2012 Nov;1822(11):1692-704
pubmed: 22885155
J Cancer. 2020 Jan 1;11(2):488-499
pubmed: 31897244
Food Chem Toxicol. 2020 Jan;135:110863
pubmed: 31604113
Neoplasma. 2020 Nov;67(6):1359-1366
pubmed: 32787437
Cancer Biother Radiopharm. 2020 Sep 9;:
pubmed: 32907349
Cancers (Basel). 2019 Jan 07;11(1):
pubmed: 30621055
Pharm Res. 2011 Dec;28(12):3091-100
pubmed: 21853360
Sci Rep. 2019 Oct 17;9(1):14913
pubmed: 31624308
Pharmacol Res. 2020 Oct;160:105199
pubmed: 32942019
Mol Med Rep. 2016 Mar;13(3):2763-8
pubmed: 26847601
Carcinogenesis. 2020 Mar 13;41(1):2-7
pubmed: 31711135
Cancer Res. 2013 Sep 1;73(17):5519-31
pubmed: 23811941
Apoptosis. 2014 Apr;19(4):708-18
pubmed: 24370994
Int J Mol Sci. 2020 Jun 03;21(11):
pubmed: 32503307
Cancer Chemother Pharmacol. 2020 Feb;85(2):413-423
pubmed: 31907648
Onco Targets Ther. 2016 Sep 12;9:5643-50
pubmed: 27672335
Life Sci. 2020 Oct 15;259:118239
pubmed: 32784058
PLoS One. 2012;7(6):e39520
pubmed: 22761812
Anticancer Drugs. 2016 Mar;27(3):147-55
pubmed: 26682525
Autophagy. 2020 Jul;16(7):1236-1247
pubmed: 31448672
BMC Complement Med Ther. 2020 Jun 23;20(1):194
pubmed: 32576183
Oncol Lett. 2019 Dec;18(6):6491-6500
pubmed: 31814849
Mol Ther Nucleic Acids. 2018 Jun 1;11:455-467
pubmed: 29858080
FEBS Lett. 2008 Jan 9;582(1):54-67
pubmed: 18022395
Acta Pharm. 2020 Sep 1;70(3):399-409
pubmed: 32074070
Cancer Lett. 2018 Oct 10;434:1-10
pubmed: 29969658
J Thorac Oncol. 2009 Jun;4(6):674-8
pubmed: 19461400
Int J Mol Sci. 2016 Aug 10;17(8):
pubmed: 27517917
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1722-1729
pubmed: 31032663
Int J Cancer. 2010 Apr 1;126(7):1630-9
pubmed: 19795445
Cancers (Basel). 2018 Dec 03;10(12):
pubmed: 30513925
Cell Commun Signal. 2020 Sep 29;18(1):159
pubmed: 32993709
Oncol Res. 2018 Jul 5;26(6):869-878
pubmed: 29212574
Anticancer Drugs. 2020 Sep;31(8):776-784
pubmed: 32796403
Cancer Manag Res. 2020 May 25;12:3845-3850
pubmed: 32547220
Cell. 2018 Feb 8;172(4):841-856.e16
pubmed: 29395328
Clin Transl Oncol. 2020 Jan;22(1):111-121
pubmed: 31667686
J Cell Mol Med. 2020 Sep;24(17):9560-9573
pubmed: 32672418
Anesth Analg. 2020 Oct;131(4):1270-1280
pubmed: 32925348
Toxicol Lett. 2018 Oct 1;295:124-133
pubmed: 29864457
Science. 2013 Jul 26;341(6144):395-9
pubmed: 23888040
Lung Cancer. 2014 Feb;83(2):146-53
pubmed: 24331411
Breast Cancer Res Treat. 2009 Jan;113(2):217-30
pubmed: 18266105
Cancer Discov. 2020 Jan;10(1):72-85
pubmed: 31594766
Cell Signal. 2021 Feb;78:109871
pubmed: 33279671
Theranostics. 2020 Feb 3;10(6):2859-2871
pubmed: 32194840
Oncotarget. 2014 Apr 15;5(7):1897-911
pubmed: 24722367
Int J Clin Exp Pathol. 2015 Feb 01;8(2):1175-83
pubmed: 25973003
Neoplasma. 2020 Mar;67(2):296-303
pubmed: 31884801
PLoS One. 2013 Jul 25;8(7):e69756
pubmed: 23936094
Biomed Pharmacother. 2016 Apr;79:93-101
pubmed: 27044817
CA Cancer J Clin. 2018 Jul;68(4):284-296
pubmed: 29809280
Biomolecules. 2019 Dec 13;9(12):
pubmed: 31847229
Biochem Biophys Res Commun. 2020 Jan 22;521(4):887-893
pubmed: 31711642
Exp Cell Res. 2020 Sep 15;394(2):112157
pubmed: 32610185
Oncotarget. 2016 May 10;7(19):27007-20
pubmed: 27105503
Clin Transl Oncol. 2014 Aug;16(8):708-13
pubmed: 24293118
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2866-2874
pubmed: 31299862
Toxicol Mech Methods. 2020 Mar;30(3):197-207
pubmed: 31682781
Biochem Pharmacol. 2005 Mar 1;69(5):811-8
pubmed: 15710358
Int J Clin Exp Pathol. 2019 Nov 01;12(11):4011-4023
pubmed: 31933797
Clin Exp Pharmacol Physiol. 2020 Aug;47(8):1464-1472
pubmed: 32198770
Mol Cell. 2019 Nov 7;76(3):516-527.e7
pubmed: 31492635
Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9286-9294
pubmed: 31773696
Cell Cycle. 2020 Jan;19(2):193-206
pubmed: 31885310
J Clin Invest. 2010 Feb;120(2):485-97
pubmed: 20051626
PeerJ. 2017 Aug 25;5:e3627
pubmed: 28852584
Cancer Manag Res. 2020 Apr 16;12:2559-2566
pubmed: 32368137
Oncol Rep. 2020 Mar;43(3):897-907
pubmed: 32020207
Oncol Rep. 2018 Apr;39(4):1631-1639
pubmed: 29484437
Oncotarget. 2017 Jul 12;8(38):63911-63922
pubmed: 28969040
Anticancer Agents Med Chem. 2019;19(8):1058-1068
pubmed: 30727918
Biomed Pharmacother. 2019 Mar;111:1103-1111
pubmed: 30841423
Biochem Cell Biol. 2019 Dec;97(6):722-730
pubmed: 30970220
Oncotarget. 2016 Dec 20;7(51):84508-84519
pubmed: 27811366
Shock. 2019 Nov;52(5):513-521
pubmed: 30407372
Tumour Biol. 2016 Nov;37(11):15315-15324
pubmed: 27699665
Cancer Res. 2017 Nov 15;77(22):6168-6178
pubmed: 28935812
J Adv Res. 2020 Jul 13;26:83-94
pubmed: 33133685
Cancer Biol Ther. 2019;20(7):989-998
pubmed: 30983514
Int J Mol Sci. 2015 Jan 30;16(2):3148-62
pubmed: 25647415
J Biol Chem. 2006 Jul 21;281(29):19881-91
pubmed: 16670091
Molecules. 2020 Dec 04;25(23):
pubmed: 33291686
Cell Stem Cell. 2007 Nov;1(5):555-67
pubmed: 18371393
Int J Oncol. 2015 May;46(5):2011-20
pubmed: 25695913
Oncotarget. 2017 Jan 31;8(5):7231-7247
pubmed: 27980227
Cold Spring Harb Perspect Med. 2020 May 1;10(5):
pubmed: 31712221
Clin Chim Acta. 2010 Jun 3;411(11-12):846-52
pubmed: 20223231
Onco Targets Ther. 2020 Sep 16;13:9147-9157
pubmed: 32982303
Neoplasma. 2020 Jan;67(1):102-110
pubmed: 31777256
Life Sci. 2020 Sep 15;257:118040
pubmed: 32622943
Oncotarget. 2015 Mar 10;6(7):5147-63
pubmed: 25762616
Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188449
pubmed: 33058996
Neurosci Res. 2020 Sep 28;:
pubmed: 32991951
Int Immunopharmacol. 2020 Apr;81:106035
pubmed: 31753588
Nutr Cancer. 2020;72(6):1057-1066
pubmed: 31573354
Biochem Biophys Res Commun. 2013 Nov 1;440(4):604-10
pubmed: 24099768
In Vitro Cell Dev Biol Anim. 2018 Oct;54(9):621-628
pubmed: 30132256
Oncogene. 2005 Nov 14;24(50):7410-25
pubmed: 16288288
Cancer Sci. 2008 Sep;99(9):1820-6
pubmed: 18544087
Cancer Lett. 2018 Mar 28;417:152-160
pubmed: 29306016
Curr Opin Immunol. 1998 Oct;10(5):559-63
pubmed: 9794836
Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118624
pubmed: 31837982
Oncol Rep. 2019 Dec;42(6):2550-2560
pubmed: 31638259
Thorac Cancer. 2020 Jan;11(1):156-165
pubmed: 31777195
Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9480-9488
pubmed: 31773700
Onco Targets Ther. 2019 Dec 16;12:11097-11105
pubmed: 31908478
Molecules. 2017 Feb 13;22(2):
pubmed: 28208828
Cell. 2007 Jan 12;128(1):157-70
pubmed: 17218262
J Clin Invest. 2014 Sep;124(9):3807-24
pubmed: 25083991
Science. 1997 Jul 25;277(5325):567-70
pubmed: 9228007
J Cell Physiol. 2019 Dec;234(12):23596-23607
pubmed: 31236953
Mol Cancer. 2019 Dec 10;18(1):181
pubmed: 31823788
Adv Sci (Weinh). 2020 Sep 24;7(21):2002518
pubmed: 33173749
Mol Cancer. 2019 Jun 22;18(1):111
pubmed: 31228937
Biochem Cell Biol. 2020 Oct 24;:
pubmed: 33103467
Eur Rev Med Pharmacol Sci. 2018 Jun;22(11):3408-3414
pubmed: 29917192
Invest New Drugs. 2020 Jun;38(3):558-573
pubmed: 31177399
Sci Rep. 2017 Aug 21;7(1):9022
pubmed: 28827662
J Biol Chem. 2006 Jul 21;281(29):19798-808
pubmed: 16682409
Cancer Manag Res. 2019 Nov 11;11:9529-9540
pubmed: 31807077
Cancer Cell Int. 2019 Dec 9;19:331
pubmed: 31827405
Oncol Rep. 2018 Jul;40(1):272-282
pubmed: 29767245
Cancers (Basel). 2018 Jul 10;10(7):
pubmed: 29996471
Front Cell Dev Biol. 2020 Dec 01;8:590478
pubmed: 33335899
PLoS Biol. 2009 Jan 20;7(1):e17
pubmed: 19166270
Phytother Res. 2014 Oct;28(10):1553-60
pubmed: 24831732
Mol Med Rep. 2020 Feb;21(2):597-606
pubmed: 31974591
Cell. 2006 Mar 24;124(6):1111-5
pubmed: 16564000
Front Genet. 2020 Jan 14;10:1278
pubmed: 32010177
Somat Cell Mol Genet. 1990 Nov;16(6):593-8
pubmed: 2267632
Exp Ther Med. 2020 Jan;19(1):400-408
pubmed: 31853317
Cancer Cell Int. 2019 Oct 7;19:257
pubmed: 31624470
Mol Cell Biochem. 2011 Jun;352(1-2):197-207
pubmed: 21359530
Med Sci Monit. 2020 Mar 02;26:e920981
pubmed: 32115570
Sci Rep. 2020 Jul 29;10(1):12685
pubmed: 32728066
Exp Cell Res. 2019 Dec 1;385(1):111597
pubmed: 31525340
Cancer Res. 2013 Sep 1;73(17):5402-15
pubmed: 23856247
Molecules. 2019 Apr 22;24(8):
pubmed: 31013639
PLoS One. 2012;7(3):e32476
pubmed: 22427843
Tumour Biol. 2015 Sep;36(9):6965-72
pubmed: 25861022
J Cell Mol Med. 2019 Dec;23(12):8114-8127
pubmed: 31599500
PLoS One. 2014 Jun 06;9(6):e99067
pubmed: 24905916
Cancers (Basel). 2018 Nov 08;10(11):
pubmed: 30413072
Cell Death Dis. 2017 May 18;8(5):e2796
pubmed: 28518139
Cell Oncol (Dordr). 2019 Dec;42(6):739-756
pubmed: 31396859
J Mol Med (Berl). 2014 Mar;92(3):267-76
pubmed: 24233024
Cell Death Dis. 2020 May 5;11(5):320
pubmed: 32371982
Oncol Rep. 2017 Nov;38(5):3064-3070
pubmed: 28901474
Cancer. 2019 Apr 15;125(8):1228-1246
pubmed: 30748003
Br J Pharmacol. 2017 Dec;174(24):4684-4700
pubmed: 28736855
Clin Exp Pharmacol Physiol. 2020 Mar;47(3):503-516
pubmed: 31788833
Oncotarget. 2017 Mar 21;8(12):19172-19191
pubmed: 27880728
EPMA J. 2020 Jul 30;11(3):377-398
pubmed: 32843908
Biomolecules. 2019 Dec 06;9(12):
pubmed: 31817720
Pharmaceutics. 2020 Nov 11;12(11):
pubmed: 33187385
Am J Transl Res. 2017 Apr 15;9(4):1856-1865
pubmed: 28469790
Biomed Pharmacother. 2020 Mar;123:109717
pubmed: 31865146
Cancer Treat Rev. 2018 Jan;62:29-38
pubmed: 29154023
Nat Commun. 2019 Aug 12;10(1):3637
pubmed: 31406163
PLoS One. 2014 Aug 01;9(8):e103698
pubmed: 25084400
Phytother Res. 2020 Dec;34(12):3311-3324
pubmed: 32628350
PLoS One. 2015 Mar 23;10(3):e0121547
pubmed: 25799148
J Cell Physiol. 2019 Dec;234(12):22343-22351
pubmed: 31066051
Front Pharmacol. 2018 Dec 04;9:1294
pubmed: 30564115
Mol Med Rep. 2014 Feb;9(2):541-6
pubmed: 24337320
Front Pharmacol. 2020 Sep 02;11:1250
pubmed: 32982725
Arch Biochem Biophys. 2020 Aug 15;689:108412
pubmed: 32445778
Life Sci. 2020 Aug 1;254:117238
pubmed: 31887300
DNA Cell Biol. 2017 Nov;36(11):976-982
pubmed: 28872922
Mol Cell Biochem. 2013 Jan;372(1-2):35-45
pubmed: 22956424
J Cancer. 2017 Mar 7;8(5):870-879
pubmed: 28382150
Pathol Res Pract. 2020 Jan;216(1):152731
pubmed: 31785995
Nutr Cancer. 2016;68(1):154-64
pubmed: 26771440
J Cancer. 2019 Oct 15;10(24):6037-6047
pubmed: 31762813
Med Sci Monit. 2019 Mar 30;25:2311-2319
pubmed: 30926767
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):548-554
pubmed: 30849921
Oncol Lett. 2020 Jan;19(1):805-812
pubmed: 31897197
Cancer Biother Radiopharm. 2019 Nov;34(9):559-565
pubmed: 31436472
Int J Oncol. 2020 Aug;57(2):445-455
pubmed: 32626932
Phytomedicine. 2020 Jan;66:153109
pubmed: 31790894
Neoplasma. 2020 Mar;67(2):249-258
pubmed: 31973533
Oncol Lett. 2017 Jun;13(6):4825-4831
pubmed: 28599484
Tumour Biol. 2016 Jun;37(6):8145-52
pubmed: 26715274
Breast Cancer Manag. 2019 Oct 18;8(3):BMT29
pubmed: 31857826
Breast Cancer Res Treat. 2012 Aug;134(3):933-41
pubmed: 22350790
Theranostics. 2019 Oct 18;9(26):8206-8220
pubmed: 31754391
Int J Clin Exp Pathol. 2015 Apr 01;8(4):3827-34
pubmed: 26097565
BMB Rep. 2009 Jun 30;42(6):350-5
pubmed: 19558793
Panminerva Med. 2020 Jun 04;:
pubmed: 32506887
Cytotechnology. 2017 Aug;69(4):667-680
pubmed: 28321778
Aging (Albany NY). 2019 Nov 26;11(22):10374-10384
pubmed: 31772141
Genomics. 2021 Jan;113(1 Pt 1):398-410
pubmed: 33301895
Cell Mol Life Sci. 2019 May;76(10):1947-1966
pubmed: 30879091
Cancers (Basel). 2019 Feb 22;11(2):
pubmed: 30813295
J Exp Clin Cancer Res. 2019 Feb 8;38(1):62
pubmed: 30736829
Cancer Sci. 2020 Sep;111(9):3279-3291
pubmed: 32619088
Sci Rep. 2019 Dec 23;9(1):19619
pubmed: 31873114
J Exp Clin Cancer Res. 2019 Jun 13;38(1):256
pubmed: 31196157
Gene. 2021 Jan 15;766:145113
pubmed: 32891771
Br J Cancer. 2020 Jun;122(12):1732-1743
pubmed: 32327707
Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H685-92
pubmed: 14551058
Mol Ther. 2020 Sep 2;28(9):2083-2095
pubmed: 32526202
BMC Pulm Med. 2020 Aug 24;20(1):223
pubmed: 32838785
Oncol Lett. 2019 Nov;18(5):4621-4628
pubmed: 31611970
Cancers (Basel). 2019 Feb 19;11(2):
pubmed: 30791487
Biomed Pharmacother. 2017 Sep;93:570-579
pubmed: 28686971
J Clin Pathol. 2020 Oct;73(10):636-641
pubmed: 32060074
Biomed Pharmacother. 2016 Jul;81:79-85
pubmed: 27261580
Biochim Biophys Acta Mol Cell Res. 2020 Sep;1867(9):118731
pubmed: 32360668
Molecules. 2019 Aug 28;24(17):
pubmed: 31466313
Mol Med Rep. 2020 Jun;21(6):2589-2596
pubmed: 32236614
Clin Cancer Res. 2010 Jan 1;16(1):45-55
pubmed: 20028757
Cancer Lett. 2008 Dec 8;272(1):102-9
pubmed: 18703276
Biosci Rep. 2020 Jan 31;40(1):
pubmed: 31763681
Biomedicines. 2020 Aug 03;8(8):
pubmed: 32756305
J Cell Biochem. 2019 Apr;120(4):5666-5676
pubmed: 30335891
Aging (Albany NY). 2019 Nov 13;11(21):9689-9708
pubmed: 31719211
Cancer Cell. 2009 Dec 8;16(6):498-509
pubmed: 19962668
Oncol Rep. 2017 Oct;38(4):2401-2407
pubmed: 28765915
J Cancer. 2020 Jan 1;11(6):1325-1333
pubmed: 32047539
Biomolecules. 2020 Jul 12;10(7):
pubmed: 32664703
Biomolecules. 2020 Aug 07;10(8):
pubmed: 32784711
Pathol Res Pract. 2020 Jan;216(1):152762
pubmed: 31836324
Pharmacol Res. 2019 Dec;150:104504
pubmed: 31678208
Int J Mol Sci. 2020 Apr 27;21(9):
pubmed: 32349289
Chem Biol Interact. 2017 Nov 1;277:33-42
pubmed: 28844858
Theranostics. 2019 Oct 22;9(26):8321-8331
pubmed: 31754399
Onco Targets Ther. 2019 Mar 12;12:1947-1956
pubmed: 30881046
Gene. 2017 Jan 5;596:110-118
pubmed: 27746366
Sci Rep. 2016 Jul 21;6:30005
pubmed: 27445062
J Cell Mol Med. 2018 Apr;22(4):2478-2487
pubmed: 29392841
PLoS One. 2013;8(3):e59563
pubmed: 23533633
Biomolecules. 2020 Oct 05;10(10):
pubmed: 33027960
Cell Physiol Biochem. 2012;30(3):631-41
pubmed: 22832383
Cell Biosci. 2018 Mar 22;8:23
pubmed: 29588850
Cancer Prev Res (Phila). 2013 Aug;6(8):843-54
pubmed: 23803415
J Cancer. 2016 Dec 9;7(15):2408-2419
pubmed: 27994679
Biomedicines. 2018 Jul 27;6(3):
pubmed: 30060453
Biochem Cell Biol. 2020 Jun;98(3):426-433
pubmed: 31742423
Cell Prolif. 2020 Aug;53(8):e12867
pubmed: 32596964
Cancer Manag Res. 2019 Dec 19;11:10599-10608
pubmed: 31908532
Oncotarget. 2020 Jul 14;11(28):2793-2806
pubmed: 32733649
Antioxid Redox Signal. 2016 Aug 20;25(6):283-99
pubmed: 27400860
Int J Med Sci. 2020 Aug 25;17(15):2292-2298
pubmed: 32922194
Biomed Res Int. 2020 May 9;2020:9512793
pubmed: 32775453
Nat Commun. 2019 Sep 26;10(1):4375
pubmed: 31558756
Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7
pubmed: 21037258
J Cell Physiol. 2020 Apr;235(4):3309-3319
pubmed: 31587272
Clin Transl Oncol. 2021 Feb 10;:
pubmed: 33566305
Cancer. 2007 Jun 15;109(12 Suppl):2667-711
pubmed: 17503436
Mol Cancer Ther. 2014 Feb;13(2):444-53
pubmed: 24258346
J Cell Biochem. 2019 Dec 1;:
pubmed: 31788846
Int J Biochem Cell Biol. 2019 Mar;108:17-20
pubmed: 30630112
Med Oncol. 2019 Nov 12;37(1):4
pubmed: 31713081
Cancer Cell Int. 2019 Nov 8;19:283
pubmed: 31719796
Nanotechnology. 2020 May 1;31(18):185102
pubmed: 31952056
Cancer Biother Radiopharm. 2020 Aug 4;:
pubmed: 32757994
Cancers (Basel). 2019 Oct 15;11(10):
pubmed: 31619007
Molecules. 2018 Jul 02;23(7):
pubmed: 30004418
Cell Death Dis. 2020 May 29;11(5):405
pubmed: 32471980
J Biol Chem. 2017 Apr 7;292(14):5801-5813
pubmed: 28232485
J Cell Biochem. 2020 Feb;121(2):1664-1674
pubmed: 31680294
Cancers (Basel). 2019 Nov 25;11(12):
pubmed: 31769419
Aging (Albany NY). 2019 Dec 9;11(23):11369-11381
pubmed: 31819016
Cancer Lett. 2015 Jul 10;363(1):28-36
pubmed: 25827070
Gene. 2018 Mar 20;647:13-20
pubmed: 29309884
Eur Rev Med Pharmacol Sci. 2020 Apr;24(7):3624-3632
pubmed: 32329837
Onco Targets Ther. 2020 May 04;13:3717-3728
pubmed: 32440141
Mol Cancer Ther. 2017 Nov;16(11):2528-2542
pubmed: 29021293
PLoS One. 2014 Jul 24;9(7):e103305
pubmed: 25058005
Molecules. 2020 Feb 06;25(3):
pubmed: 32041140