Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care.
fetal progenitor fibroblasts
optimized cell banking
pediatric second-degree burns
progenitor biological bandages
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
28 Feb 2021
28 Feb 2021
Historique:
received:
22
01
2021
revised:
22
02
2021
accepted:
23
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
7
3
2021
Statut:
epublish
Résumé
Progenitor Biological Bandages (PBB) have been continuously applied clinically in the Lausanne Burn Center for over two decades. Vast translational experience and hindsight have been gathered, specifically for cutaneous healing promotion of donor-site grafts and second-degree pediatric burns. PBBs constitute combined Advanced Therapy Medicinal Products, containing viable cultured allogeneic fetal dermal progenitor fibroblasts. Such constructs may partly favor repair and regeneration of functional cutaneous tissues by releasing cytokines and growth factors, potentially negating the need for subsequent skin grafting, while reducing the formation of hypertrophic scar tissues. This retrospective case-control study (2010-2018) of pediatric second-degree burn patients comprehensively compared two initial wound treatment options (i.e., PBBs versus Aquacel
Identifiants
pubmed: 33671009
pii: ph14030201
doi: 10.3390/ph14030201
pmc: PMC7997469
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
Références
Burns. 2006 Dec;32(8):992-9
pubmed: 16901651
Tissue Eng Part B Rev. 2013 Feb;19(1):1-13
pubmed: 23253031
Int J Burns Trauma. 2017 Dec 20;7(7):124-141
pubmed: 29348976
Dev Biol. 1995 May;169(1):242-60
pubmed: 7750642
Proteomics. 2003 Aug;3(8):1521-5
pubmed: 12923777
Clin Exp Obstet Gynecol. 2004;31(3):167-73
pubmed: 15491058
Methods Mol Biol. 2021;2286:49-65
pubmed: 32572700
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Jul;54(7):811-5
pubmed: 21698533
J Burn Care Res. 2013 Mar-Apr;34(2):e60-79
pubmed: 23446645
Skin Pharmacol Physiol. 2009;22(2):94-102
pubmed: 19188757
Biomedicine (Taipei). 2015 Dec;5(4):22
pubmed: 26615539
J Surg Res. 2010 Nov;164(1):e115-23
pubmed: 20828761
Front Cell Dev Biol. 2020 Dec 17;8:547653
pubmed: 33392179
Burns. 2018 May;44(3):549-559
pubmed: 29183637
Ann Burns Fire Disasters. 2017 Jun 30;30(2):95-102
pubmed: 29021720
PLoS One. 2020 Mar 4;15(3):e0229455
pubmed: 32130238
Ther Clin Risk Manag. 2010 Feb 02;6:21-7
pubmed: 20169033
Pathol Biol (Paris). 2002 Mar;50(2):65-73
pubmed: 11933836
Methods Mol Biol. 2021;2286:25-48
pubmed: 32468492
Lancet. 2014 Mar 29;383(9923):1168-78
pubmed: 24034453
ANZ J Surg. 2004 Aug;74(8):622-6
pubmed: 15315558
Tissue Eng Part A. 2011 Jan;17(1-2):5-15
pubmed: 20726816
Mol Ther. 2013 Feb;21(2):261-2
pubmed: 23369962
Clin Interv Aging. 2007;2(1):93-8
pubmed: 18044080
Cytotherapy. 2016 Jun;18(6):797-805
pubmed: 27068764
Cytotherapy. 2014 Mar;16(3):289-97
pubmed: 24113428
Clin Plast Surg. 2017 Jul;44(3):627-634
pubmed: 28576252
Tissue Eng Part A. 2012 Nov;18(21-22):2187-94
pubmed: 22838399
Clin Plast Surg. 1985 Apr;12(2):149-57
pubmed: 3886257
Cytotherapy. 2014 Dec;16(12):1597-600
pubmed: 25293816
Swiss Med Wkly. 2019 May 19;149:w20079
pubmed: 31104308
Adv Drug Deliv Rev. 2018 Jan 1;123:1-2
pubmed: 29273168
Rev Med Suisse. 2010 Feb 17;6(236):354-7
pubmed: 20229727
Skin Pharmacol Physiol. 2009;22(2):63-73
pubmed: 19188754
Am J Obstet Gynecol. 1991 Jan;164(1 Pt 1):218-30
pubmed: 1670910
J Immunol. 1990 May 1;144(9):3354-60
pubmed: 1691755
Skin Res Technol. 2014 May;20(2):218-27
pubmed: 24033842
Cell Transplant. 2006;15(8-9):823-34
pubmed: 17269452
J Pediatr Surg. 1997 Mar;32(3):411-5
pubmed: 9094005
Front Bioeng Biotechnol. 2020 Jun 19;8:581
pubmed: 32637400
J Tissue Eng Regen Med. 2015 Jun;9(6):649-68
pubmed: 24668923
Adv Wound Care (New Rochelle). 2019 Nov 1;8(11):555-564
pubmed: 31637102
Cell Transplant. 2007;16(7):675-84
pubmed: 18019357
JAMA. 2013 Nov 27;310(20):2191-4
pubmed: 24141714
Burns. 1994;20 Suppl 1:S52-5; discussion S55-6
pubmed: 8198745
Crit Care. 2015 Jun 12;19:243
pubmed: 26067660
Burns. 2017 Jun;43(4):733-740
pubmed: 28040360
Cell Tissue Bank. 2013 Dec;14(4):525-60
pubmed: 24052113
Lancet. 2005 Sep 3-9;366(9488):840-2
pubmed: 16139659
Development. 1992 Jan;114(1):253-9
pubmed: 1576963
Cell Transplant. 2019 Nov;28(11):1404-1419
pubmed: 31407589
J Burn Care Rehabil. 1990 May-Jun;11(3):256-60
pubmed: 2373734
Artif Organs. 2008 Jul;32(7):509-18
pubmed: 18638304
Methods Mol Biol. 2021;2286:1-24
pubmed: 32430595
N Engl J Med. 1984 Aug 16;311(7):448-51
pubmed: 6379456
Plast Reconstr Surg Glob Open. 2015 Feb 06;3(1):e284
pubmed: 25674365
Front Bioeng Biotechnol. 2020 Oct 23;8:557758
pubmed: 33195124
Burns Trauma. 2018 May 28;6:13
pubmed: 29854856
Swiss Med Wkly. 2009 Sep 19;139(37-38):535-9
pubmed: 19838870
Exp Gerontol. 2009 Mar;44(3):208-18
pubmed: 19049860
Viruses. 2018 Feb 06;10(2):
pubmed: 29415431
J Pediatr Surg. 2001 Aug;36(8):1118-21
pubmed: 11479839
Ann Burns Fire Disasters. 2016 Jun 30;29(2):111-115
pubmed: 28149232
PLoS One. 2013 Jul 24;8(7):e70408
pubmed: 23894651
Transfus Med Hemother. 2016 Sep;43(5):344-352
pubmed: 27781022
Proc Natl Acad Sci U S A. 1979 Nov;76(11):5665-8
pubmed: 293669
Biomaterials. 2004 Jun;25(14):2807-18
pubmed: 14962559