Taccalonolides: A Novel Class of Microtubule-Stabilizing Anticancer Agents.
anticancer agent
drug resistance
microtubule stabilizer
taccalonolide
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
22 Feb 2021
22 Feb 2021
Historique:
received:
16
01
2021
revised:
17
02
2021
accepted:
19
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
7
3
2021
Statut:
epublish
Résumé
Microtubule stabilizing agents, such as paclitaxel, docetaxel, and cabazitaxel have been among the most used chemotherapeutic agents in the last decades for the treatment of a wide range of cancers in the clinic. One of the concerns that limit their use in clinical practice is their intrinsic and acquired drug resistance, which is common to most anti-cancer chemotherapeutics. Taccalonolides are a new class of microtubule stabilizers isolated from the roots of a few species in the genus of
Identifiants
pubmed: 33671665
pii: cancers13040920
doi: 10.3390/cancers13040920
pmc: PMC7926778
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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