Self-Reported Nonadherence to Medication Is Not Associated with Health-Related Quality of Life in Parkinson's Disease.

German Stendal Adherence with Medication Score Parkinson’s disease motor impairment nonadherence quality of life unified Parkinson’s disease rating scale

Journal

Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646

Informations de publication

Date de publication:
22 Feb 2021
Historique:
received: 18 01 2021
revised: 12 02 2021
accepted: 18 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 7 3 2021
Statut: epublish

Résumé

Nonadherence is a growing issue in the treatment of Parkinson's disease (PD). Many factors are known to influence nonadherence, but little is known about the influence of quality of life (QoL). Detailed clinical data were obtained from 164 patients with PD using the Parkinson's Disease Questionnaire-39 (PDQ-39) and the German Stendal Adherence with Medication Score (SAMS). Descriptive statistics were used to identify reasons for nonadherence, and multivariable linear models were used to study associations between QoL and clinical parameters as well as nonadherence. Multivariate analysis of variance (MANOVA) and multivariate analysis of covariance (MANCOVA) were used to study the effect of the SAMS on PDQ domains and other medical covariates. The results showed that 10.4% (

Identifiants

pubmed: 33671679
pii: brainsci11020273
doi: 10.3390/brainsci11020273
pmc: PMC7926683
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Bundesministerium für Bildung und Forschung
ID : 01GY1804

Références

Curr Med Res Opin. 2009 Sep;25(9):2303-10
pubmed: 19635045
Parkinsonism Relat Disord. 2019 Sep;66:151-157
pubmed: 31409572
Heart Lung. 2019 Mar - Apr;48(2):105-110
pubmed: 30384984
Mov Disord. 2018 Oct;33(10):1601-1608
pubmed: 30145797
Int J Older People Nurs. 2018 Sep;13(3):e12196
pubmed: 29665241
J Am Geriatr Soc. 2005 Apr;53(4):695-9
pubmed: 15817019
J Neurol Sci. 2017 Mar 15;374:26-31
pubmed: 28088312
J Neurol Neurosurg Psychiatry. 2006 Feb;77(2):249-51
pubmed: 16421131
Mov Disord. 2009 Apr 30;24(6):826-32
pubmed: 19191340
Neurosci Biobehav Rev. 2016 Feb;61:26-34
pubmed: 26645499
Parkinsonism Relat Disord. 2019 Aug;65:86-90
pubmed: 31118162
Med Care. 2004 Mar;42(3):200-9
pubmed: 15076819
Value Health. 2016 Mar-Apr;19(2):277-85
pubmed: 27021763
Front Neurol. 2019 Jul 31;10:799
pubmed: 31417484
Neurol Neurochir Pol. 2019;53(2):123-130
pubmed: 30807640
Int J Environ Res Public Health. 2020 Jan 06;17(1):
pubmed: 31935851
Rev Saude Publica. 2016 Dec 22;50:71
pubmed: 28099657
Mov Disord. 2005 Nov;20(11):1502-7
pubmed: 16037924
Mov Disord. 2000 Mar;15(2):216-23
pubmed: 10752569
Res Social Adm Pharm. 2019 Dec;15(12):1419-1424
pubmed: 30772239
Mov Disord. 2015 Oct;30(12):1591-601
pubmed: 26474316
Qual Life Res. 2019 Apr;28(4):1053-1061
pubmed: 30470970
Front Med (Lausanne). 2020 Mar 25;7:103
pubmed: 32269998

Auteurs

Hannah M Zipprich (HM)

Department of Neurology, Jena University Hospital, 07747 Jena, Germany.

Sarah Mendorf (S)

Department of Neurology, Jena University Hospital, 07747 Jena, Germany.

Thomas Lehmann (T)

Center for Clinical Studies, Jena University Hospital, 07747 Jena, Germany.

Tino Prell (T)

Department of Neurology and Center for Healthy Ageing, Jena University Hospital, 07747 Jena, Germany.

Classifications MeSH