Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications.
dental applications
mechanical pro-perties
poly(ether ether ketone)
zinc oxide nanoparticles
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
23 Feb 2021
23 Feb 2021
Historique:
received:
06
01
2021
revised:
12
02
2021
accepted:
19
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
7
3
2021
Statut:
epublish
Résumé
The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications.
Identifiants
pubmed: 33672249
pii: ma14041047
doi: 10.3390/ma14041047
pmc: PMC7926823
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Consejo Nacional de Ciencia y Tecnología
ID : A1-S-34231
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : Discovery grant to Diego Mantovani
Organisme : Canadian Foundation of the Innovation
ID : Infrastructure grant to DM
Organisme : Ministry of International Relations of the Quebec Province
ID : Linkage grant to Diego Mantovani
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